COPD: Microbial Pattern in Acute Exacerbation in Tertiary Care
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 12
Abstract
Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of morbidity and mortality worldwide. The natural history of COPD is characterized by frequent exacerbations. Majority of exacerbations are infectious and knowledge on the pattern of infectious bacteria and their antibiotic sensitivity is essential to formulate cost-effective antibiotic strategy and reducing the emergence of drug resistance. Fifty sputum samples from clinically diagnosed COPD cases suffering from acute exacerbation were collected to isolate and identify the aerobic bacterial agents causing acute exacerbations in COPD patients, to study the antibiotic sensitivity patterns of the isolates and phenotypic detection of ESBL production by the isolates. Preparation of media, reagents, Gram staining, identification of culture isolates, different tests including antibiotic sensitivity tests were carried out following standard laboratory procedures. Klebsiella pneumonia and Escherichia coli were the commonest bacteria isolated followed by Pseudomonas, Citrobacter and anaerobic species (5). All the isolates of K.pneumoniae were ESBL producers. Periodic isolation and identification and resistant status of pathogens causing AECOPD will help us to formulate appropriate treatment protocol and this will be of immense use in reducing mortality and morbidity besides reducing the volume of antibiotics and development of resistance to antibiotics.(6)
Authors and Affiliations
Muthukumar Shunmugam
Keywords
Related Articles
- EP ID EP210291
- DOI -
- Views 58
- Downloads 0
Autoamputation of Penis Following A Fournier’s Gangrene – A Rare Occurrence
Fournier’s gangrene is a type of polymicrobial necrotizing fasciitis involving perineal, perianal and urogenital region, especially the scrotum but rarely involves the penis. The penis is relatively spared of this life t...
Propofol – A Gallery of Different Formulations and Methods to Alleviate Pain on Injection
Propofol is a popular intravenous (IV) anaesthetic agent both for induction and maintenance. The initial formulations were potent lipid emulsions; efforts to overcome their drawbacks have altered propofol preparation ove...
Assessment of Antioxidant activity in Brassica oleracea var. capitata rubra
Brassica oleracea var. capitata rubra extract with different solvents [methanol, ethanol. Water, acetone and chloroform] were analyzed for antioxidant activities. The antioxidant activities were evaluated based on the ab...
Surgery induced Astigmatism following Nonphaco Manual Small incision Cataract Surgery in relation to different Postoperative period
Purpose-To find out surgery induced astigmatism following SICS at the end of first week, third week, and sixth week during the study period from 2013-2014. Materials and Methods; Cataract surgeries were carried out in pa...
The Role of Bronchoscopy in the Diagnosis of Sputum Smear Negative Pulmonary Tuberculosis
Introduction: Diagnosis of sputum/smear-negative pulmonary tuberculosis patients can be both challenging and time consuming with many patients being put on empirical anti-tubercular treatment. Bronchoscopy may provide a...