COPD Treatment in Real Life and Randomized Controlled Trials: Is There Any Difference between Both Settings?
Journal Title: Chronic Obstructive Pulmonary Disease: Open Access - Year 2017, Vol 2, Issue 1
Abstract
In the last decade, for treatment of patients with chronic obstructive pulmonary disease (COPD) a myriad of new medications, mostly administered in new inhalation devices were introduced on the market. In addition, All, but one (Roflumilast) of these “new” drugs rely on old and well proven principles of long acting bronchodilation. Nonetheless, for gaining regulatory approval many randomized controlled trials (RCT’s) were accomplished for long-acting beta2 agonists (LABA’s) and long-acting anticholinergics (LAMA’s) and their fixed combinations, respectively, Inhaled corticosteroids (ICS) as anti-inflammatory therapy are available on the market for a long time, but their indication for COPD is controversial [1,2] and new fixed combinations emerged. Hence even more RCT’s for pharmacological treatment of COPD were recently completed. Therefore, enough high grade evidence from RCT’s should exist for pharmacological treatment of COPD patients.
Authors and Affiliations
Peter Kardos
Keywords
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- EP ID EP304098
- DOI 10.21767/2572-5548.100020
- Views 21
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