Coronary Artery Disease With Hyperurecemia In Type 2 Diabetes Mellitus
Journal Title: National Journal of Medical and Dental Research - Year 2017, Vol 5, Issue 4
Abstract
Background:Hyperuricemia or elevated serum uric acid level (SUA) is a biochemical entity that is gaining increasing importance as a cardiovascular risk factor. Hyperuricemia has been reported to be associated with the onset of diabetes mellitus or metabolic syndrome. Several studies have reported the relationship between HUA and diabetic macroangiopathies, such as coronary heart disease, stroke and peripheral arterial disease. Objectives:To study and Compare mean Serum Uric Acid levels in Patients of both Known & New Case Of Diabetes Mellitus on with presence and absence of Coronary Artery Disease (CAD). Materials and methods:All the patients satisfying the inclusion and exclusion criteria were grouped as under as Known cases i.e. Patients of type II Diabetes Mellitus with or without CAD, New cases i.e. .Patients of type II Diabetes Mellitus with or without CAD. All the patients were studied for the following variables such as Age (Years) BMI (kg/m2) ,Body Mass index, FBS(mg/dl) PPBS(mg/dl) HbA1C (%) : Glycosylated haemoglobin, Serum Uric acid levels (mg/dl). Results: 55.20% of known cases of type 2 DM and 26.20% of new cases of type 2 DM were with Coronary Artery Disease (CAD). The mean serum Uric acid levels were high 6.37mg/dl is patients of known cases of type 2 DM with Coronary Artery Disease (CAD) where as 5.37mg/dl in new cases of type 2 DM with Coronary Artery Disease (CAD). Hyperuricemia i.e.mean serum uric acid above 7mg/dl was highly significant in cases of type 2 DM with Coronary Artery Disease (CAD). Conclusion: The mean Serum Uric acid levels were found higher in known cases of type 2 DM with CAD then with newly diagnosed cases revealing Hyperuricemia in CAD. Thus it can be very well concluded that Hyperuricemia can be predictor or risk factor for CAD in type 2 Diabetes mellitus.
Authors and Affiliations
Vineet Kumar Shravastava, Milind Chandurkar, Rahul Kunkulol
Keywords
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