CORRECTION OF ACTIVITY OF THE ANTIOXIDANT PROTECTION SYSTEM IN VARIOUS TYPES OF HIGH NERVOUS ACTIVITY BY THE TECHNOLOGICAL STRESS
Journal Title: Ukrainian Journal of Veterinary Sciences - Year 2018, Vol 1, Issue 285
Abstract
Nanoparticles of biogenic metals have a greater biological activity than their molecular forms. The aim of the research was to determine the effect of nanochelates Mg, Zn, Ge and Ce on the activity of the antioxidant system in pigs of different types of higher nervous activity by the action of a technological stimulus. It was established that the activity of superoxide dismutase and catalase in red blood cells of pigs of different types of higher nervous activity to the effect of technological stimuli is not significantly different. After the action of a technological stimulus, the activity of superoxide dismutase in red blood cells of pigs is reduced by 15.7-21.8% (p <0.05-0.01), depending on the type of higher nervous activity. As a result of the presentation of pigs to nanoaquachelates, the effect of the technological stimulus to a lesser extent influenced the activity of enzymes, thus, the activity of superoxide dismutase in animals of a strong, well balanced mobile, strong, balanced inert, severe unbalanced and weak type of higher nervous activity decreases during the day, respectively, by 3.9%, 10.8 %, 16.5% (p <0.05) and 16.4% (p <0.05). Thus, the activity of superoxide dismutase in blood red blood cells of a strong, well-balanced, mobile, strong, balanced, inert, strong, unbalanced and weak type of higher nervous activity of the experimental group was higher (although within the trend) by 14.0%, 9.4%, 5.2 % and 7.0% of the indexes of their analogues from the control group. Due to the release of biogenic metal nanochelates, the effect of the technological stimulus contributed to the inadequate reduction of catalase activity in red blood cells of pigs of different types of higher nervous activity (by 0.6-9.5%). The activity of catalase in erythrocytes of these animals was higher in the range of 5.7-10.3% of the indexes of their analogues from the control group. Thus, the release of nanoparticles of metals significantly reduces the effect of the technological stimulus on the activity of superoxide dismutase and catalase in red blood cells of pigs.
Authors and Affiliations
О. V. Danchuk, V. І Karpovsky
Keywords
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