Correlates the Biochemical Markers of Ovarian Neoplasm, Experience From A Tertiary Care Setting in A City Of India.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 5
Abstract
Most ovarian neoplasms are benign, epithelial types are commonest. There is no regular screening test for detecting malignant ovarian neoplasm, most patients remain asymptomatic until late stages. About 80% of malignant ovarian neoplasm present in stage 3 and 4 with 15% 5 year survival rate. To find out frequency of different types of ovarian neoplasm among women aged 15-60 years and correlates ovarian neoplasm among benign and malignant neoplasms and compare levels of tumour markers among subjects with benign and malignant neoplasms. A Cross sectional descriptive study conducted in a tertiary care setting, city of Eastern India, women aged 15- 60 years with ovarian neoplasm. 131 selected study subjects interviewed with predesigned schedule, levels of tumour markers CA-125 and β-hCG estimated. Final analysis done on 112 histopathologically confirmed cases. Data analyzed in SPSS version 16.0. Most ovarian neoplasms were benign (65%). Histopathologically commonest serous cyst adenoma (25%), serous cyst adenocarcinoma (23.22%). Malignant neoplasm had significant association with urban residence (56.41%) (p=0.048), menopause (53.84%) (p=0.005) and serum CA-125(p=0.0001). Patients with gynaecological comorbidities found suffering more benign ovarian neoplasm (p=0.01). Postmenopausal women have more chance of having malignant ovarian neoplasm than benign neoplasm.
Authors and Affiliations
Dr. Sukla Nath, Dr. Mallika Biswas, Dr. Swati Bhattacharyya, Dr. Tarun Biswas
Keywords
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- EP ID EP598151
- DOI 10.9790/0853-1605111620
- Views 87
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