Correlation between HDL-C and Nitric Oxide in Normal Healthy Population
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 7
Abstract
Prevention of coronary artery disease (CAD) and reduction of its mortality and morbidity remains a major public health challenge throughout the world. Nitric oxide (NO) plays a pivotal role in CAD (coronary artery diseases).This study was undertaken to show the correlation between HDL& NO in normal healthy population since decreased NO bioavailability is a key feature of all classic risk factors for Atherosclerosis. A cross sectional study was done with sample size 60. In this study it was found that lower Nitric oxide is significantly associated with higher level of HDL with P<0.001. We conclude that constantly low HDL-C concentration is related with endothelial dysfunction and increased oxidative stress in healthy young men, consistent with the idea that HDL particles may protect endothelium and inhibit the oxidation of LDL. These findings may offer insight into increased atherosclerosis associated with low HDL-C levels.
Authors and Affiliations
Ratna Priya
Keywords
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