CORRELATION BETWEEN HEMOGLOBIN A1C LEVEL AND FASTING BLOOD GLUCOSE LEVEL: A SUMMARY ON THE REPORTS IN THE SETTING WITH HIGH PREVALENCE OF HEMOGLOBIN DISORDER
Journal Title: Acta Facultatis Medicae Naissensis - Year 2012, Vol 29, Issue 2
Abstract
The investigation of hemoglobin A1C is presently accepted as a tool for the evaluation of the glycemic control in the diabetic patients. However, due to the high cost, it is limitedly used in many developing countries. The old classical approach, fasting blood glucose determination, is still the standard method in those countries. There are many reports showing the correlation between hemoglobin A1C level and fasting blood glucose level. An interesting point is that there is a limited assessment on those reports, especially in the setting with possible problems of using hemoglobin A1C due to the interference from hemoglobin disorder. In this work, the author performed a meta-analysis by fixed effect model to summarize the reports on the correlation between hemoglobin A1C level and fasting blood glucose level in the setting with high prevalence of hemoglobin disorder, Thailand. The databases PUBMED (from 1910 to February 2012), Cochrane Library (from 1993 to February 2012) and Thai Index Medicus (from 1918 to February 2012) were used for searching the time span. Only four specific reports on the correlation between hemoglobin A1C level and fasting blood glucose have been found. All reports are homogeneous presenting a poor correlation between the two parameters. Of overall 1,207 diabetic cases, a pooled correlation coefficient is equal to 0.48. The result shows that the poor correlation might be due to the high prevalence of hemoglobin disorder in this setting. This might imply that fasting blood glucose might not be used to imply hemoglobin A1C in the areas with the background of endemic hemoglobin disorder.
Authors and Affiliations
Viroj Wiwanitkit
Keywords
Related Articles
- EP ID EP141813
- DOI 10.2478/v10283-012-0012-8
- Views 84
- Downloads 0
EKSPERIMENTALNA ELISA NE DAJE ZADOVOLJAVAJUĆE REZULTATE U DIJAGNOSTICI PERI-ORBITALNE DIROFILARIOZE
Vrste D. repens i D. immitis, paraziti pasa, dugo poznati kao uzročnici zoonoza, mogu kao nezrele jedinke da parazitiraju i u organizmu čoveka. Na dirofilarioze, najčešće asimptomatske infekcije, posumnja se u slučaju su...
Developmentand Validation of a Questionnaire about Patient Knowledge of Adverse Effects of Statins - - - Dizajn i validacija upitnika za procenu znanja bolesnika o neželjenim dejstvima statina
Statins are drugs that are well tolerated, but considering their extensive use, there are still concerns regarding their safety. Knowledge of patients about the side effects of statins has not been adequately studied, al...
NEW DRUGS FOR OSTEOPOROSIS THERAPY: A REVIEW OF THE CLINICAL TRIALS PHASE 2 AND 3
Osteoporosis is a chronic disease with increasing incidence that predominantly occurs in female population. There are evidences that bisphosphonates, selective estrogen receptor modulators, denosumab, teriparatide and st...
MEDICAL STUDIES IN ENGLISH: SHARED LEARNING
In recent years, medical studies in English have been organized at the Niš Faculty of Medicine. Thus, modern teaching approaches are required. It has been shown that there are many similarities between the two fields - E...
Akutni efekti pušenja na srčanu frekvenciju i periferni otpor kod mladih osoba
Pušenje ima mnogo štetnih efekata na ljudski organizam. Dobro je poznato da pušenje predstavlja jedan od najvažnijih faktora rizika za pojavu kardiovaskularnih bolesti. Sastojci dima cigarete stimulišu oslobađanje vazo...