Developmentand Validation of a Questionnaire about Patient Knowledge of Adverse Effects of Statins - - - Dizajn i validacija upitnika za procenu znanja bolesnika o neželjenim dejstvima statina
Journal Title: Acta Facultatis Medicae Naissensis - Year 2016, Vol 33, Issue 4
Abstract
Statins are drugs that are well tolerated, but considering their extensive use, there are still concerns regarding their safety. Knowledge of patients about the side effects of statins has not been adequately studied, although timely recognition of the AES is of vital importance for improving the quality of patient care and reducing morbidity and suffering. The aim of this study was to develop and test a questionnaire for measuring the knowledge of patients about statin therapy about adverse effects of statins (AES). This two-center cross-sectional study was conducted during the period from March 1, 2015 to April 1, 2016, taking place in pharmacies from the city of Belgrade and at the Department of Internal Medicine, Clinical Center in Kragujevac, Serbia. The study included 300 patients and 20 pharmacists. The questionnaire showed satisfactory internal consistency, with Cronbach’s alpha of 0.898, good construction and homogeneity of questions. After splitting the questionnaire to two parts at random, Cronbach’s alphas were 0.834 and 0.842 for the both parts, respectively. Exploratory factorial analysis revealed two domains. The patients rated their knowledge of the side effects of statins 52.7±19.9 on the visual analogue scale. Based on the results of this study, we believe that this questionnaire could be a useful tool for testing the knowledge of patients about adverse effects of statins and help physicians to identify patients with insufficient knowledge who should be additionally informed about it. - - - - Statini su lekovi koji se dobro tolerišu i s obzirom na njihovu veliku upotrebu, još uvek postoje brige o njihovoj bezbednosti. Znanje bolesnika o neželjenim dejstvima statina nije do sada adekvatno ispitivano iako je rekognicija neželjenih dejstava od vitalnog značaja za poboljšanje kvaliteta brige o bolesniku smanjenjem morbiditeta i patnje bolesnika. Cilj ovog rada bio je da razvije i testira validirani pouzdan upitnik koji bi merio znanje bolesnika koji su naterapiji statinima o njegovim neželjenim dejstvima. Ova multicentrična studija preseka je sprovedena u perioduod 01.03.2015. do 01.04.2016. u apotekama na teritoriji grada Beograda i na Klinici za internu medicinu Kliničkog centra u Kragujevcu. Studijom je obuhvaćeno 300 bolesnika i 20 farmaceuta. Skala „Znanjebolesnika o neželjenim dejstvima statina“ pokazala je visoku pouzdanost sa vrednošću Kronbahovog koeficijenta od 0.898, dobru konstrukciju i homogenost pitanja. Prilikom nasumičnog deljenja upitnika na dva dela, vrednosti alfe su bile 0.834 i 0.842. Eksplorativna faktorska analiza je ukazala na postojanje dva faktora. Bolesnici su svoje ukupno znanje o neželjenim dejstvima statina ocenili sa 52.7± 19.9 na vizuelno-analognoj skali. Na osnovu rezultata ove studije, verujemo da bi ovaj upitnik mogao biti korisno sredstvo za ispitivanje znanja bolesnika o neželjenim dejstvima statina i možepomoći lekarima da identifikuju bolesnike sa nedovoljnim znanjem koji bi trebalo da se dodatno informišu.
Authors and Affiliations
Valentina Opačina, Slobodan Janković, Gordana Stanić, Miljan Opačina
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