Correlation between Serum Vitamin D Levels and BODE Index in COPD Patients in A Tertiary Care Centre
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 3
Abstract
Abstract: Chronic Obstructive Pulmonary Disease (COPD) is a preventable and treatable disease and a major cause of disability and death all over the world. A multidimensional scale, the BODE index [BMI (B), degree of airflow obstruction (O), dyspnea as measured by the MRC dyspnea scale (D), and exercise capacity (E)] has been validated and proven to be useful in predicting two year mortality. Vitamin D deficiency is commonly seen in COPD patients. This study conducted in a tertiary care hospital has focused on the relationship between serum vitamin D levels and BODE index. A cross sectional observational study was performed at Nizam’s Institute Of Medical sciences, a tertiary care hospital in Hyderabad, Telangana during the period of 2015-2017.This study included 104 COPD cases attending outpatient department of pulmonary medicine. Among 104 patients, 87 were males and 17 were females. The mean Vitamin D value of the study population was 20.77ng/ml (±11.74). Most of the patients (60%) had BODE index score < 5.The mean BODE index score decreased as the degree of vitamin D deficiency increases. Serum vitamin D deficiency is present in majority of COPD patients .It is more prevalent among patients with higher COPD GOLD Stages. There appears to be a positive correlation between serum vitamin D levels and post bronchodilator FEV1 (%). Vitamin D deficiency was found to be positively correlated with 6 minute walk distance. There is significant correlation between serum vitamin D deficiencies and BODE index.
Authors and Affiliations
Laxma Reddy S, Bhaskar K, Vara Prasad K, Paramjyothi GK
Keywords
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