CORRELATION BETWEEN UMBILICAL CORD BLOOD VOLUME WITH GESTATIONAL AGE AND BIRTH WEIGHT: A BASELINE FOR CORD BLOOD BANKS IN PAKISTAN
Journal Title: Baqai Journal of Health Sciences - Year 2018, Vol 21, Issue 2
Abstract
Placental vessels contain one-third of newborn blood volume termed as umbilical cord blood (UCB). It is an enriched product with many benefits but unfortunately, it is usually discarded as waste. Since the identification of its benefits, many countries have established Cord Blood Banks using UCB for transfusion and transplantation. Despite having a high fertility rate, no such facility is currently present in Pakistan. UCB is used as autologous blood and can also be used as a homologous source. In this study, 200 UCB units (250 ml blood bags; anticoagulant volume adjusted) were collected, volume obtained was calculated and correlated with gestational age and birth weight. Pearson’s correlation coefficient has been applied on means that showed a strong positive relationship. In addition, different hematological and biochemical parameters (storage lesion parameters) were measured and mean values were calculated in order to provide baseline values. The study concluded that UCB can be collected in blood bags. More the gestational age and birth weight more will be the blood volume collected. It is recommended to conduct large-scale studies regarding the collection, storage and transfusion of UCB to provide a platform for the establishment of Cord Blood Banks in Pakistan.
PHYSICOCHEMICAL PROPERTIES AND PHARMACOLOGY OF AMLODIPINE BESYLATE: A BRIEF REVIEW
Hypertension is one of the well-studied risk factors for cardiovascular diseases and the oldest class of hypertensive drugs is the calcium channel blockers. Amlodipine besylate (ADB) belongs to the dihydropyridine family...
PRE-IMPLANTATION AND PRE-GENETIC DIAGNOSIS - AN ADVANCED TOOL FOR THE FORTHCOMING GENERATION
Genetic disorders are a major cause of miscarriage and fetal death. Pre-implantation genetic diagnosis (PGD) is a very useful technique which can be used to diagnose genetic defects before pregnancy. It can be done by cr...
A REVIEW ON THE ANALYTICAL TECHNIQUES USED FOR THE DETERMINATION OF PARACETAMOL IN PHARMACEUTICAL FORMULATIONS AND BIOLOGICAL FLUIDS
Paracetamol (PM) is an active metabolite of phenacetin and belongs to p-aminophenol derivatives. It is also termed as acetaminophen. PM is one of the non-steroidal anti-inflammatory drugs (NSAIDs) which is used as an ana...
STUDY OF THE TOXIC EFFECTS OF CYPERMETHRIN IN EXPERIMENTAL ANIMALS
This study focuses on the toxic effects of a commercially available pesticide, cypermethrin (CM), on animals. This pesticide was administered in the form of aerosol spray through a nebulizer. The study was performed in f...
THE EVALUATION OF FREQUENCY AND SEASONAL VARIATIONS OF ACID PEPTIC DISEASE: A SEVEN YEARS STUDY
Acid peptic disease (APD) is a worldwide health problem. It includes a variety of inflammatory and ulcerative lesions involving esophagus, stomach and duodenum. The disease condition may persist with multiple symptoms, o...