Correlation of body mass index Z-scores with glucose and lipid profiles among overweight and obese children and adolescents
Journal Title: Jornal de Pediatria - Year 2018, Vol 94, Issue 3
Abstract
Objective To evaluate the prevalence of abnormalities in plasma lipid and glucose profiles among overweight and obese children and adolescents, and to assess the presence of a correlation between body mass index Z-scores and indicators of comorbidities related to both profiles. Methods This was a multicenter cross-sectional study conducted at two outpatient clinics. The study included all 417 comers for the first visit from 2008 to 2012, aged between 7 and 18 years, with BMI above the Z-score +1. Anthropometry and blood sampling were obtained. The prevalence of dyslipidemias, hyperglycemia, and insulin resistance were evaluated, together with the correlations of these variables with the increase of Z-BMI. Results Dyslipidemia was observed in 43.4% of the boys and 66.1% of the girls, with no difference between genders. High glucose levels were detected in 6.2% of the individuals. Insulin resistance was present in 32.3% and 41.7% of the cases, with no statistical significance between boys and girls. Correlations between the Z-BMI were noted for triglycerides in the entire group and among girls; for HDL-c, only among girls; for glucose, a correlation was observed for the entire group, but not when stratified by gender. The indicators of insulin resistance were all correlated with Z-BMI, even when corrected for age. Conclusions Overweight and obesity give origin to a high prevalence of dyslipidemia and insulin resistance. BMI Z-scores showed a weak positive correlation with glucose and triglyceride, and negative with HDL-c. In turn, the strongest positive correlation was found with insulin resistance indicators.
Authors and Affiliations
Carlos Alberto Nogueira-de-Almeida
Keywords
Related Articles
- EP ID EP485094
- DOI 10.1016/j.jped.2017.06.012
- Views 94
- Downloads 0
Screen time impairs the relationship between physical fitness and academic attainment in children
Objective The purpose of this study was twofold: to analyze the association between physical fitness and academic attainment, and to determine the influence of screen time on the association between physical fitness and...
Social and biological determinants of growth and development in underprivileged societies
The stimulating study by da Rocha Neves et al. (in this issue)1 addresses the role of social and biological factors in growth and development of young children in a disadvantaged society. The authors assessed a group of...
ERICA: age at menarche and its association with nutritional status
Objective To estimate the mean age at menarche and its association with nutritional status in Brazilian adolescents. Methods The study sample included female adolescents aged 12–17 who participated in a multicenter, sch...
Salivary C-reactive protein, mean platelet volume and neutrophil lymphocyte ratio as diagnostic markers for neonatal sepsis
Objective To assess the applicability of salivary C-reactive protein, mean platelet volume, neutrophil-lymphocyte ratio, and platelet lymphocyte ratio in the diagnosis of neonatal sepsis. Methods Prospective case-contro...
Fibrinogen: cardiometabolic risk marker in obese or overweight children and adolescents
Objectives To determine the prevalence of increased serum fibrinogen levels and its association with cardiometabolic risk factors in overweight or obese children and adolescents. Methods Cross-sectional study with 138 c...