Correlation of EEG, CT, and MRI Brain with Neurological Outcome at 12 Months in Term Newborns with Hypoxic Ischemic Encephalopathy
Journal Title: Pediatric Education and Research - Year 2019, Vol 7, Issue 3
Abstract
Objective: To study the correlation between electroencephalograms (EEG), computed tomography (CT), and magnetic resonance imaging (MRI) brain with neurological result at 12 months in term neonates with hypoxic ischemic encephalopathy. Design: Prospective observational study. Materials and Methods: :The study has been conducted between August 2017 and August 2018. Termneonates with perinatal asphyxia and hypoxic ischemic encephalopathy were the subjects. All babies were managed as per standard protocol in a tertiary health care hospital in NICU (Neonatal Intensive Care Unit). EEG was done as soon as the baby was stable and CT brain within 7 days. MRI was done at 3 months. Neurodevelopmental assessment was done at 1 year. Results: Out four babies died of total 31, four babies died. 15 babies showed normal neurodevelopmental results at the age of 1 year. EEG results were normal in six babies and all of them had a normal neurodevelopment. Thirteen of the 14 babies with burst suppression pattern were abnormal. CT brain reports were normal in 14 babies and all of them had normal neurodevelopment while 11 of the 12 babies with cerebral edema had abnormal outcome. Of the 16 babies with normal MRI, 14 were normal, while all six babies showing abnormal signals in the cortex and thalamus had unfavorable outcome. Conclusions: Term newborn babies with hypoxic ischemic encephalopathy (HIE) and showing normal EEG & CT Brain results is associated with good neurological outcome. Babies showing Burst suppression pattern in EEG & bleeds & or hypodensities in the CT and involvement of basal ganglia/thalamus in the MRI are predictors of unfavourableunfavorable outcome.
Authors and Affiliations
Sharda C Aher
Keywords
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- EP ID EP649453
- DOI 10.21088/per.2321.1644.7319.6
- Views 69
- Downloads 0
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