Correlation of Hypothyroidism with Pregnancy Outcome in Preeclampsia
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 4
Abstract
Background- Thyroid disorders constitute one of the most common endocrine disorders in pregnancy. It is associated with adverse maternal outcomes including eclampsia, pre-eclampsia, placental abnormalities, miscarriages, pre-term labor, and low birth weights. Material and Methods-The present study was carried out on the pregnant women in their second and third trimesters attending outpatient department of obstetric and gynaecology from October2012 to September2014. 100 Preeclamptic women were included in the study group and 50 normotensive women were included in the control group. Both groups were screened for hypothyroidism and were followed through their antenatal, intranatal and postnatal period. Results- Increased incidence of preterm labour, antepartum haemorrhage, IUGR found in cases of preeclampsia with high serum TSH. Significant negative correlation was observed between birth weight and mean arterial pressure. Positive coorelation seen between Birthweight andT4 and T3, negative coorelation between TSH and birth weight in cases of preeclampsia.No significant difference found in caeserian rate between preeclampsia with high serum TSH and those with normal serum TSH Conclusion- In the present study, serum TSH was significantly higher in preeclamptic women than in normotensive women and fT3 and fT4 were slightly lower in preeclamptic women. Also increase in serum TSH is associated with adverse maternal and fetal outcome. Hence timely intervention in term of supply of thyroid hormone may overcome these adverse effects.
Authors and Affiliations
Dr Anita Kumari Murmu, Dr Seema Kumari, Dr Amrita Sharan, Dr Surendra Baskey
Keywords
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- EP ID EP373447
- DOI 10.9790/0853-1704147278.
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