Correlation of Pap smear and colposcopic finding with directed biopsy in detection of cervical neoplasm

Abstract

Introduction: Cancer of uterine cervix is the most common genital tract malignancy. Pap smear though widely used screening test for cervical cancer has the disadvantage of low sensitivity. Colposcopy has higher sensitivity compared to Pap smear. Concurrent screening with Pap smear and colposcopy can overcome this problem. Aim: The aim of the study was correlation of Pap smear and colposcopic finding with directed biopsy in detection of cervical neoplasm. Methods: The Present study was conducted in the Department of Pathology, Gujarat Adani Institute of Medical Science, Bhuj, Kutch.During the study period in 57 symptomatic patient’s simultaneous Pap smear, colposcopic examination, followed by directed biopsy was performed. Data was recorded and analyzed. Results: In correlation between cytology and biopsy, sensitivity of cytology was 82.3%, specificity 96.9% and accuracy of 92%. In correlation between colposcopy and biopsy, sensitivity of colposcopy was 94.1%, specificity 87.8% and accuracy of 90%. Conclusion: High sensitivity in colposcopy as compared to cytology and high specificity in cytology as compared to colposcopy emphasizes the need for pairing these methods to achieve better results.

Authors and Affiliations

Jigna Upadhyay, Sameep Garg

Keywords

Related Articles

Comparative evaluation of FNAC, core needle biopsy and excisional biopsy in subtyping of breast lesions

Background: Although available literature on Fine needle aspiration cytology (FNAC) and core needle biopsy (CNB) in breast lesions are enormous but studies regarding the comparison of CNB and FNAC in palpable breast lump...

Isolation, Speciation and antifungal drug susceptibility of Candida species from clinically suspected infections in a tertiary care hospital

Introduction: The incidence of fungal infections has increased dramatically over the last two to three decades. Study was done on, Clinical samples from suspected patients of candidiasis. Study period was one and a half...

Comparative evaluation of bivalent malaria rapid diagnostic tests versus traditional microscopy method in assessment of malaria in blood donors at a tertiary care teaching hospital and regional blood transfusion centre in central India

Background: Global malaria control efforts are based on 2 broad components: vector control and improved diagnosis and treatment of patients with clinical malaria. Until recently, conventional diagnosis of malaria has bee...

An analysis of skin appendageal tumors: 10 year study

Introduction: Skin appendageal tumors are wide spectrum of disorders that differentiate towards one or more adnexal structures. Objective: To determine the prevalence of skin appengeal tumours. Materials and methods: Thi...

Ki67 expression in triple negative breast cancer: Correlation of Ki67 expression with other prognostic factors in breast cancer in Indian patients

Introduction: Triple negative breast cancer ( TNBC) cases are not sensitive to hormonal therapy and till date no specific targeted medication has been found for TNBC. The present study aims to know the expression of Ki67...

Download PDF file
  • EP ID EP264588
  • DOI 10.17511/jopm.2017.i4.06
  • Views 169
  • Downloads 0

How To Cite

Jigna Upadhyay, Sameep Garg (2017). Correlation of Pap smear and colposcopic finding with directed biopsy in detection of cervical neoplasm. Pathology Update: Tropical Journal of Pathology and Microbiology, 3(4), 396-400. https://europub.co.uk/articles/-A-264588