Correlative Studies between Computed Tomography and Magnetic Resonance Imaging Scan Findings and Histopathology of Solitary Fibrous Tumors of Abdomen and Pelvis
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 9
Abstract
Background: Solitary fibrous tumors (SFTs) are a unique group of mesenchymal neoplasms of fibroblastic or myofibroblastic origin. These tumors were originally described as “benign fibrous mesothelioma” of the pleural cavity, but presently they are being reported from all organs in the body. They are reported from abdominal organs and need to be differentiated from other solid tumors such as leiomyosarcomas, neurogenic tumors, pheochromocytomas, lymphoma, desmoid tumors, malignant fibrous histiocytomas, mesothelioma, and fibromas. Aim of the Study: The aim of the study was to study the radiological features of SFTs of abdomen and pelvis on computed tomography (CT) scan and magnetic resonance imaging (MRI) and to correlate with their pathological features retrospectively. Materials and Methods: A total of 24 patients with SFTs attending the tertiary teaching hospital were included in the study. Demographic data were collected from the case sheets for analysis. Radiological signs of CT and MRI scans from the patients were observed and correlated retrospectively with the histopathological study of excised surgical specimens to understand and standardize the characteristic features. Observations and Results: Among the 28 patients there were 18 (75%) male patients and 6 (25%) female patients. The male to female ratio was 1:3. The mean age was 42.65 ± 2.70 years. The presenting symptoms were lump in the abdomen, pain, mass in the abdominal wall, urinary obstruction, constipation and sometimes neurologic or vascular symptoms. CT and MRI scans showed round or oval, homogenous or heterogeneous and markedly enhanced lesions without secondaries. Histopathological examination showed both cellular and fibrous variants of the SFTs. Conclusions: The radiological signs of solid fibrous tissue tumors are well-defined, hypervascular masses with variable degrees of necrosis, cystic change, or hemorrhage. On MRI they manifested as heterogeneous hyperintensities on T2WI. The specimens following surgical excision retrospectively correlate well with the radiological findings in terms of vascularity and tissues content.
Authors and Affiliations
T M Sheethal Shanibi, C M Sheethal, M A Safna, Archana Ramachandran
Keywords
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