Corrigendum: Current status of immunologic approaches to treating tobacco dependence: Vaccines and nicotine-specific antibodies
Journal Title: The AAPS Journal - Year 2006, Vol 8, Issue 3
Abstract
Authors and Affiliations
Mark G. LeSage, Daniel E. Keyler, Paul R. Pentel
Pharmacodynamic parameter estimation: Population size versus number of samples
The purpose of this study was to evaluate the effects of population size, number of samples per individual, and level of interindividual variability (IIV) on the accuracy and precision of pharmacodynamic (PD) parameter e...
Evaluation of Pre-existing Antibody Presence as a Risk Factor for Posttreatment Anti-drug Antibody Induction: Analysis of Human Clinical Study Data for Multiple Biotherapeutics
Biotherapeutic-reactive antibodies in treatment-naïve subjects (i.e., pre-existing antibodies) have been commonly detected during clinical immunogenicity assessments; however information on pre-existing antibody...
Cell Cycle Checkpoint Models for Cellular Pharmacology of Paclitaxel and Platinum Drugs
A pharmacokinetic–pharmacodynamic mathematical model is developed for cellular pharmacology of chemotherapeutic drugs for which the decisive step towards cell death occurs at a point in the cell cycle, presumably...
Application of Quantitative Pharmacology in Development of Therapeutic Monoclonal Antibodies
The advancement of therapeutic monoclonal antibodies during various stages of the drug development process can be effectively streamlined when appropriate translational strategies are applied. Design of successful transl...
Functional and Molecular Aspects of Biotin Uptake via SMVT in Human Corneal Epithelial (HCEC) and Retinal Pigment Epithelial (D407) Cells
The online version of this article (doi:10.1208/s12248-012-9399-5) contains supplementary material, which is available to authorized users.