Criteria of severity for macular edema associated with retinal vein occlusion: cohort heterogeneity and efficacy evaluation of threshold and subthreshold retinal laser photocoagulation depending on the macular edema severity criteria. Part II.
Journal Title: Офтальмологический журнал - Year 2017, Vol 0, Issue 6
Abstract
Background. Macular edema (ME) develops in 60-100% of patients with retinal vein occlusion (RVO). ME becomes chronic with a decrease in visual acuity in 1/3-2/3 of patients with RVO-associated ME. The gold standard of care to treat patients with macular edema associated with RVO is retinal laser photocoagula-tion. Purpose. To develop an evaluation system for severity of macular edema asso-ciated with retinal vein occlusion on a ground of morphometrical and clinical characteristics and to compare the efficacy of threshold and subthreshold retinal laser photocoagulation depending on this evaluation. Material and Methods. A total of 160 patients (160 eyes) with RVO-associated macular edema were included in the study. Laser photocoagulation was performed not before than three months of disease onset. Subthreshold and threshold laser photocoagulation of the macula was performed in 38 and 110 patients, respectively. 12 patients had resorption of edema so they required no laser treatment. The follow-up period was twelve months. The examination methods used have been described in our previous paper. Results. The heterogeneity analysis of the cohort of patients with RVO-associated ME was proposed. The clinical burden assessment was developed and criteria of macular edema severity were defined. There were four clusters that clearly differed in their clinical and morphometric characteristics. Subthreshold laser photocoagulation was shown to be more successful for patients with significant retinal ischemia and threshold laser photocoagulation was more successful for patients with the increased foveal thickness. Conclusions. Four cluster distribution of the RVO-associated ME patients made it possible to reduce the heterogeneity of the studied cohort since the defined clusters were homogenous in severity criteria; the patients had similar values within each cluster. Subthreshold photocoagulation was best for the significant ischemic area (>5 DD). For the foveal thickness >547 µm, most successful was threshold laser photocoagulation.
Authors and Affiliations
T. Romanova
Keywords
Related Articles
- EP ID EP251807
- DOI -
- Views 85
- Downloads 0
Mistakes in the treatment of pterygium
Abrupt thinning and even perforation at the limbus and cornea due to deep pterygium excision are potential postoperative complications of pterygium syrgery. Postoperative complications were observed in 25.7% of patients...
The 70th Anniversary of Functional Diagnostics Department of Filatov Institute of Eye Diseases and Tissue Therapy of NAMS of Ukraine
On the 30th of October 2018, Department of Functional Diagnostics of the Eye at SI “Filatov Institute of Eye Diseases and Tissue Therapy of NAMS of Ukraine” celebrated the 70th Anniversary.
Patterns of development of retinal vascular pathology at remote time period after radiation exposure
Background. Retinal vascular system is extremely sensitive to ionizing radiation exposure and requires priority medical examination. Probability of new accident environmental contamination with radioactive material is a...
Optical features of light passing through refractive structures of the eye
The features of light refraction in the anterior segment of the eye and after dispersion on the posterior surface of the cornea are considered. It is shown that the cornea refracts the light as a weakly scattering lens....
Improving the technique for controlled cryogenic destruction of conjunctival tumors located in the projection of the ciliary body onto the sclera: a preliminary report
Background: In case of controlled cryogenic destruction of an epibulbar tumor, making direct temperature measurements in the tumor and surrounding tissues during the treatment process is difficult and dangerous. Infrared...