CURRENT APPROACH FOR THE TREATMENT OF PARKINSON’S DISEASE BY SIMVASTATIN: A REVIEW
Journal Title: Journal of Pharmaceutical and Scientific Innovation - Year 2017, Vol 6, Issue 6
Abstract
Parkinson disease has become one of the common life-threatening health problem in the world. But the pathogenesis and related mechanisms are still unclear. Current therapy of Parkinson’s disease (PD) is not satisfactory, which is the use of combinations of levodopa with other dopaminergic agonist but it is symptomatic in nature and does not slow down the disease course. Many studies have revealed that statins which are used as an antihyperlipidemic drug and have the ability to protect the dopaminergic cells from neurodegeneration. They have anti-inflammatory, suppression of oxidative stress, anticoagulation, angiogenesis actions. So in this review, we are trying to find out the actions of statins on Parkinson disease.
Authors and Affiliations
R Vadivelan, Richu Babu, Arun. T. Nair, Swati Sharma, T. Jyothsna
Keywords
Related Articles
- EP ID EP453312
- DOI 10.7897/2277-4572.06666
- Views 60
- Downloads 0
A REVIEW ON STANDARD MILK HYGIENE PRACTICES IN INDIA WITH SPECIAL REFERENCE TO CLEAN MILK PRODUCTION
Milk is the complete food. It contains in a balanced form of all the necessary and digestible elements for building and maintaining the human and animal body. In addition, it contains immunoglobulins which protect the ne...
MULTIPLE UNIT PELLET SYSTEM (MUPS TECHNOLOGY) FOR DEVELOPMENT OF MODIFIED RELEASE FAST DISINTEGRATING TABLETS: A REVIEW
Oral drug delivery system becomes challenging when the drug product needs to be delivered in modified release pattern in elderly patients, especially since it is difficult to swallow for them. Multiparticulates are the c...
CHITOSAN AS A COATING AGENT ON THE DRUG ELUTING STENTS TO PREVENT BIOFILM FORMATION DURING STENT IMPLANTATION
Arteriosclerosis is the build-up of fatty cells and tissues within blood vessels. Coronary stents implantation is considered as a common method for atherosclerosis cases. Formation of neointimal tissue and high infection...
DRUG USE PATTERN AMONG DIABETIC HOSPITALIZED PATIENTS MANAGED WITH ORAL HYPOGLYCEMIC DRUGS, INSULIN, BOTH ORAL HYPOGLYCEMIC DRUGS AND INSULIN IN TERTIARY CARE TEACHING HOSPITAL
To observe and document the drug use pattern in hospitalized diabeticpatients. To determine the choice of therapy based on age, gender, complications, duration of the disease. To find out the commonly occurring adverse d...
ANTIBACTERIAL ACTIVITY OF MURCHITA AND AMURCHITA ARKA TAILA PREPARED WITH DIFFERENT RATIOS OF KALKA: AN INVITRO STUDY
Appearance carries a lot in modern world. Human beings are very much aware about the way they present before others. Vicharchika (eczema) is one of the most common skin problems and bacterial infection is one of the caus...