Current global approach to quality control swine erysipelas vaccines by “potency”
Journal Title: Бюлетень "Ветеринарна біотехнологія" - Year 2017, Vol 30, Issue
Abstract
Introduction. One of the main areas of veterinary science and practice is the development and production of diagnostic and preventive means protecting the country from agents introduction of especially dangerous animal diseases. In this regard, provision the practice of veterinary medicine with therapeutic effective and preventive preparations is one of the main issue. The goal of the work was to analyze and determine compliance of the basic methods of quality control of vaccines against swine erysipelas by of "potency" in the European Union (EU), United States and acting currently in Ukraine. Materials and methods. International and national guidelines concerning the quality of veterinary immunological preparations against swine erysipelas were analysed. Results of research and discussion. Studies indicated that under international guidelines it is expected to use the reference preparations that has been tested with positive results for by "immunogenicity" in the target animal species. However, today in Ukraine this approach for quality control of inactivated vaccine against erysipelas is not available. Conclusions and prospects for further research: 1. For the purpose of harmonization with international recommendations quality control methods inactivated vaccine against swine erysipelas, must take into account the positive experience of the European Union on the use of reference preparations during quality control of vaccines produced series. 2. Analysis of the main methods of quality control of inactivated and lived vaccines against swine erysipelas in the European Union (EU) and active at this time in Ukraine, showed some differences in the basic approach to quality control by of "potency". 3. It is necessary to implement comprehensive research on the selection of candidates in control of epizootic isolates Er. rhusiopathiae, selected from different regions of Ukraine, and create standard culture infecting Er. rhusiopathiae serotypes 1 and 2 for the quality control of vaccines against swine erysipelas.
Authors and Affiliations
Natalia Pinchuk
Keywords
Related Articles
- EP ID EP272351
- DOI 10.31073/vet_biotech30-25
- Views 132
- Downloads 0
Fusarium fungy ability to produce T-2 toxin
Introduction. The study and distribution of Fusarium fungi in feed from different regions of Ukraine and in different periods of the year is very important. Only in the presence of data on the distribution of certain fun...
Determination of bacterial contamination indices of sausage products in Odessa
The bacteriological study of sausages was carried out under conditions of agro-food markets and supermarkets in Odessa. It was established that the bacteriological contamination of sausages that did not meet the veterina...
Validation of the method for determining histamine in fish and fish products by the method of liquid chromatography using an uv detector and derivatization
Introduction. Histamines are biogenic amines that are formed in fish and fish products during the decarboxylation of histidine with the involvement of enzymes that produce microflora with impaired storage conditions. His...
Probiotic potency of Aerococcus viridans on biomodel of white mice organism
Introduction. Aerococcus viridans is a ubiquitous resident representative of the normal microbiocenosis of open cavities in animals and humans, an indicator of the health status of the macroorganism in relation to the qu...
Fusarioses among pigs
Introduction. Microscopic fungi can affect feeds at various stages of production and cause animal mycotoxicoses. The presence of mycotoxins in feeds even in trace amount can lead to considerable losses due to reduced pro...