Current Opinion in the Treatment of Diabetic Nephropathy
Journal Title: Nephrology – Open Journal - Year 2015, Vol 1, Issue 2
Abstract
Diabetic nephropathy is a leading cause of end-stage renal failure. Approximately 20-40% patients with diabetes mellitus will develop nephropathy with a significant proportion requiring regular dialysis or kidney transplantation. The International Diabetes Federation estimates that 366 million people had diabetes worldwide in 2011 and 552 million people will have this disease by 2030.1 The increasing incidence of diabetes elevates diabetic nephropathy to one of the most important current public health issues, representing a significant burden on the health system.2 Despite current interventional strategies being intensively implemented, the number of patients with diabetes requiring renal replacement therapy for end-stage renal disease is growing.3 Current treatments of diabetic nephropathy slow its progression,3 so the optimal therapeutic strategy to arrest or reverse the nephropathy is needed urgently. As multiple risk factors and their interactions promote the development of diabetic nephropathy, targeting a single factor may be ineffective in the treatment of this disease; thus, optimal treatments by targeting multiple factors need to be developed to arrest or reverse the diabetic nephropathy.
Authors and Affiliations
Xin-Ming Chen
Keywords
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- EP ID EP558151
- DOI 10.17140/NPOJ-1-104
- Views 192
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