Current Trend of the Antibiogram of Salmonella Isolates at a Tertiary Care Hospital in North India
Journal Title: Scholars Academic Journal of Biosciences - Year 2016, Vol 4, Issue 8
Abstract
Typhoid fever continues to remain a major public health problem, especially in developing due to poor sanitation and personal hygiene. Salmonella enteric serovarstyphi and Paratyphi A&B are predominantly known to cause enteric fever. A changing antibiotic susceptibility pattern of Salmonella typhi and Salmonella Paratyphi A& B and emergence of multi drug resistance has increased to a great concern. This study was conducted at the department of microbiology in Dr. RML Hospital, New Delhi to investigate the antibiotic susceptibility pattern of Salmonella typhi and Salmonella Para typhiA&B. Blood culture samples were collected from suspected enteric fever patient and tested microbiologically by standard procedure. Antibiotic susceptibility test was performed by Kirby-Bauer disc diffusion method and results were interpreted according toCLSI guidelines. Out of the total 19,037 blood samples, 228 Salmonella isolates were isolated. Of these, 206 (90.3%) were S.typhi, 21 (9.21%) isolates were S.paratyphi A and 1 isolate (0.44%) was S.paratyphi B. Among the tested antibiotics S. typhi was susceptible towards amikacin (97.5%), Chloramphenicol (89.4%), Ceftriaxone (87.8%), cotrimoxazole (87.8%), gentamicin (72.4%) followed by ciprofloxacin (10.3%) and nalidixic acid (9.1%). 2.92% of S. typhi isolates showed multidrug resistance. A considerable variation was observed in the antimicrobial susceptibility pattern of S.typhiand S.paratyphi A & B. Hence antibiotic susceptibility test must be sought before instituting appropriate therapy to prevent fromfurther emergence of drug resistance. Keywords: Typhoid fever, Salmonella typhi, Blood culture, Antimicrobial susceptibility, Chloramphenicol, Multidrug resistance.
Authors and Affiliations
Dr. Saumya Agarwal, Dr. Nandini Duggal, Dr. Arun Wilson
Keywords
Related Articles
- EP ID EP372458
- DOI -
- Views 77
- Downloads 0
Molecular Phylogenetics of Moringaceae Martinov with Emphasis on Ethnomedicinal Plant Moringa oleifera Lam. Grown in Egypt
Abstract: The monogeneric family Moringaceae is remarkable for the great diversity of habit and floral morphology within its only genus; Moringa. The aim of the present study is to infere the phylogenetic relationships o...
Effect of Chloropyrifos and Malathion on Stress and Osmolyte Parameters in Tomato and Brinjal
With the ever- increasing population and escalating demand for food, scientists are toiling hard to enhance the production level through the introduction of new high yielding cultivars, effective cultural practices and a...
Environmental impacts of mining on biodiversity of Angul - Talcher open mining site, Odisha, India
Biodiversity sustains human livelihoods and life itself. An estimated 40 per cent of the global economy is based on biological products and processes. As the biodiversity harbours a great amount of diversity with respect...
Nutritional Status and its Relation with Disease Activity in Rheumatoid Arthritis: A Study from North India
This study proposed to assess the nutritional status of RA patients and to study any impact of disease activity (as assessed by DAS 28 score) on it. In this study 150 cases of RA diagnosed according to 1987 revised ACR c...
Facilitatory Effects of Kinesio Taping on Forearm Extensors in Improving Hand Grip and Pinch Grip Strength
Abstract:Kinesio taping methods are widely used in sports and in rehabilitation as a means to improve muscle strength. The present study aims to determine the immediate and delayed, facilitatory effects of kinesio taping...