CUTANEOUS MANIFESTATIONS OF LUPUS ERYTHEMATOSUS FROM A TERTIARY CARE CENTRE IN COASTAL KERALA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 44
Abstract
BACKGROUND The aim of this study was to describe the Lupus Erythematosus (LE)-specific and LE-nonspecific cutaneous manifestations of lupus erythematosus. MATERIALS AND METHODS Cutaneous manifestations of lupus erythematosus in forty consecutive patients with LE who attended Dermatology department from January 2014 to June 2015 were studied. RESULTS Majority of the patients included in the study were female (65%). The most common age group affected was 20-40 years (47.5%). Photosensitivity was the most common symptom (45%). Forty five percent of patients in the study were diagnosed of systemic lupus erythematosus (SLE) according to the ACR criteria. LE-specific skin lesions were more common than LE-nonspecific lesions (95% vs. 40%). Chronic Cutaneous LE (CCLE) was the most common LE-specific skin lesion (85%). Only psoriasiform type of Subacute Cutaneous LE (SCLE) lesions were seen in the study group. Malar rash was the most common Acute Cutaneous LE (ACLE) lesion (87.5%). Features suggestive of systemic involvement were most commonly found in patients with ACLE and least in those with CCLE. Most common LE nonspecific lesion was non-scarring alopecia (32.5%) due to telogen effluvium. Cutaneous vascular disease in the form of palpable purpura of leucocytoclastic vasculitis (2.5%), periungual telangiectasia (7.5%), erythema multiforme (2.5%) and leg ulcers (5%) were the other LE- nonspecific skin lesions observed in the study. Patients with LEnonspecific skin lesion had more systemic involvement compared to those without it. CONCLUSION LE-specific lesions are more common and can act as a diagnostic clue for lupus. LE-nonspecific lesions are more commonly associated with systemic disease.
Authors and Affiliations
Joice James, Sandhya Somasekharan Nair
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