Cytogenetic an Experimental Monitoring Test for Plant Extracts
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2017, Vol 12, Issue 1
Abstract
More than two centuries have been passed since the chromosomes have been firstly observed in plant cells by Nageli in 1842. During this long period, chromosomes have been discovered in human cells and well recognized as a source of genes locations. The effects of chemicals and environmental pollution in human health and caners became an interested field of studying diver mutagens and their role in affecting the genetic materials. Cytogenetic tests were the main tools to evaluate the effects of those mutagens on human genome and chromosomes. Many techniques have been used for these purposes including in vitro and in vivo analyzing tests using human and animal cells. The intent of this article is to review the role of cytogenetic techniques in detecting the effects of mutagens on chromosomal aberrations and the role of plant extracts in monitoring these effects.
Authors and Affiliations
Dhamraa W. AL-Dulaimi,, Sarah F. Faisal, Hussein M. Baharetha,, Amin Malik Shah Abdul Majid
Plant Regeneration from Nodal explants Culture through Organogenesis in Eupatorium triplinerve vahl
An efficient plant regeneration protocol was developed for Eupatorium triplinerve Vahl, an important medicinal herb. Nodal explants inoculated on Murashige and Skoog medium supplemented with 4.44 μM 6-Benzyladenine(BA),...
Formulation and Characterization of Meloxicam Loaded Microspheres Intended for the Treatment of Rheumatoid Arthritis
The present work was to prepare and evaluate colon specific meloxicam loaded microspheres for the treatment of rheumatoid arthritis. Sodium alginate microspheres were prepared by using emulsification method using differe...
The Effect of Omeprazole Drug on the Blood Picture of Laboratory Rat Rattus Norvegicus
In the current study the long-term effect of omeprazole was determined by measuring some hematological parameters .Three groups of laboratory rats were taken each group (6) individual, the first groups was the control, s...
Modeling, Simulation, Docking Studies of Tyrosine Kinase Involved in Leukemia and Microwave Synthesis of Quinazoline Derivatives
Acute Mylenoid Leukemia is a type of cancer which affects blood and bone marrow and is characterized by an abnormal proliferation of white blood cells. A number of genes are involved in regulating heamatopoiesis, and the...
Prevalence Of Types Of Anemia In Pediatric Population – An Observational Study
Anemia is a very serious health problem in India and most common nutritional problems in many parts of the world. We estimated the different types of prevalence of anemia in children, an observational study. We collected...