CYTOHISTOLOGIC CORRELATION OF LUNG SPACE OCCUPYING LESIONS (SOL)- A STUDY OF 72 CASES IN A TERTIARY CARE HOSPITAL
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 3
Abstract
BACKGROUND Lung carcinoma is one of the commonest malignancies with high mortality and morbidity. Recent epidemiological studies indicate increasing incidence of lung carcinoma in India. The objectives of the study were to evaluate the clinico-pathological profile of patients of lung carcinoma in a tertiary care hospital and to correlate between cytological and histological diagnoses of the tumours. MATERIALS AND METHODS A study of patients presenting with lung mass between March 2016 and February 2017 (one year) was performed. Guided fine needle aspiration cytology (FNAC) was performed in each case and core needle biopsy was done whenever feasible. Statistical Analysis Used- The data was compiled using Microsoft Word Excel 2007. Kappa statistic test and percentage agreement was done and Kappa coefficient was derived. Study Settings and Design- It was a descriptive type of study. RESULTS A total of 72 patients were included. The ratio of male-to-female patients was 6: 1. The age of the patients ranged between 41 and 82 years with preponderance in age group of 61 - 70 years (44.4%). Computed tomography (CT) guided FNAC was done in all cases. Non-neoplastic lesions were found in 8 (11.11%) and neoplastic lesions in 64 (88.88%) cases. Among the neoplastic lesions, adenocarcinoma was diagnosed in 34 cases (62.96%), squamous cell carcinoma in 14 (25.92%), metastatic lesion in 5 (9.26%) and neuroendocrine carcinoma in 1 case (1.85%). Fifty (78.1%) patients of lung carcinoma were smokers. The right lung was involved in 38 (60%), the left in 19 (30%) and both lungs in 7 (10%) cases. Core needle biopsy was undertaken in 43 cases. Consistent histopathologic findings were obtained in 40 cases. CONCLUSION Smoking constitutes an important, yet avoidable cause of lung carcinoma. The delineation of clinico-pathologic profile of patients of a particular area is essential for determination of preventive and therapeutic strategies. FNAC can be considered as a highly useful tool for diagnosis of lung mass.
Authors and Affiliations
Pratyusha Bhattacharjee, Himansu Roy, Partha Pratim Sinha Roy
Keywords
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- EP ID EP284640
- DOI 10.14260/jemds/2018/71
- Views 71
- Downloads 0
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