Cytological Analysis of Pleural Effusion - A Five Year Retrospective Study
Journal Title: International Journal of Contemporary Medical Research - Year 2016, Vol 3, Issue 3
Abstract
Introduction: Cytological examination of pleural fluid is considered less invasive than biopsy, more simple, inexpensive, allows faster diagnosis and it facilitates in cancer screening in some cases. Cytological examination of pleural fluid is of great diagnostic value in both non neoplastic and neoplastic effusions. Aim of the study was to retrospectively analyse, all the pleural effusions, to get prevalence of benign and malignant pleural effusions and to evaluate the cytological value of pleural fluid in the diagnosis of benign and malignant lesions. Materials and Methods: Total 240 cases collected from all the patients who underwent thoracocentasis. Data were collected and analysed. From the received fresh sample, 10ml fluid was taken and fluid was centrifuged at 2500 rpm for 15 minutes and smears were prepared from the sediment and stained with MGG stain and H and E. Results: In the study of 240 cases of pleural effusion the age of patient ranged between 17-87 years. The male to female sex ratio was 1:1.1.The maximum numbers of cases were in the age group of 41-50 years, constituting 54 cases (22.4%) of the total cases (Table 1). Most of the pleural effusion were associated with benign conditions (84.6%). The rest (15.4%) of the effusions showed malignant aetiology. Amongst the malignant effusions adenocarcinoma was the most common type of secondary (70.3%, 26 cases out of 37). Conclusion: Cytological examination of pleural fluids is the most effective procedure to differentiate between benign and malignant effusion and also to know primary site of lesion in many cases.
Authors and Affiliations
Sudha Iyengar, Jagannath Jatav
Keywords
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