Assessment of Effect of Ondansetron and Metoclopramide in the Treatment of Post-Surgical Vomiting: A Comparative Study
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 1
Abstract
Introduction: Post-operative nausea and vomiting episodes are one of the common unwanted phenomenons encountered by the patients after major surgical procedures. Ondansetron and metoclopramide are the commonly used drugs for controlling the post-operative nausea and vomiting. Hence, we undertook the present study to compare the effect of ondansetron 4mg and metoclopramide 10 mg in patients undergoing major surgical procedures. Material and methods: The present study was conducted in the department of surgery of Sukh Sagar Medical college and hospital, Jabalpur and included assessment of all the patients who underwent any major surgical procedure from January 2015 to November 2016. All the patients were randomly divided into two study groups. Group 1 included patients that were administered ondansetron while group 2 included patients in which metoclopramide, intra muscular, was administered. The total number of emetic episodes was assessed in all the patients of both the groups starting 15 minutes after the surgery upto 24 hour after the surgery. Results: In group 1 and group 2, 25 and 30 patients were males respectively. Mean age of the patients in group 1 and group 2 was 44.5 and 45.8 years respectively. Mean weight of the patients in group 1 and group 2 was 64.2 and 62.8 Kg respectively. Significant result was obtained while comparing the gender of the patients in the two study groups. Conclusion: In the prevention of post-operative vomiting episodes, ondansetron is superior in comparison with metoclopramide.
Authors and Affiliations
Girish Kumar Pathak, Vishal Kalia, Naveen Sahu
Keywords
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