Cytoreductive Surgery and Hyperthermic İntraperitoneal Chemoterapy for Advance Gastric Cancer Associated Peritoneal Carcinomatosis Single Centre Unit for 10 Consecutive Patients
Journal Title: The Medical Bulletin of Haseki - Year 2019, Vol 57, Issue 3
Abstract
Aim: Hyperthermic intraperitoneal chemotherapy with cytoreductive surgery has a positive effect on survival in advanced abdominal cancers. We aimed to present our experience with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in gastric cancer patients with peritoneal carcinomatosis and a review of the literature. Methods: Ten patients (seven male, three female) who were diagnosed with gastric cancer between June 2017 and November 2018 were included in the study. Data on demographic characteristics, short-term follow-up results, surgical findings, peritoneal carcinomatosis index score, completeness of cytoreduction score, and morbidity and mortality rates were retrospectively analyzed. Results: The mean age of the patients was 60.3 years. The mean follow-up period was six months (1-15 months). One patient developed an anastomotic leak. In the other nine cases, there was no morbidity leading to mortality. Conclusion: While gastric cancer with peritoneal carcinomatos has a poor survival, less than six months with non-operative approach, treatment with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy offers better outcomes and overall survival. Our first results in our study with a limited number of patients are satisfactory and multicentric randomized studies are needed on this subject.
Authors and Affiliations
Özgül Düzgün, Sema Yüksekdağ, Murat Kalın, Şenol Çomoğlu, Semra Yanık, Ömer Faruk Özkan, Neşet Köksal
Keywords
Related Articles
- EP ID EP50767
- DOI 10.4274/haseki.galenos.2019.4997
- Views 286
- Downloads 0
Factors Associated with Insufficient Endometrial Sampling in Postmenopausal Women
Aim: To assess the risk factors associated with high rate of insufficient endometrial sampling on endometrial biopsy in postmenopausal women. Methods: Data were retrieved from the records of 522 consecutive patients who...
Assesment of Inflammatory Markers and Epicardial Adipose Tissue Thickness in Women with Polycystic Ovary Syndrome
Aim: Polycystic ovary syndrome (PCOS), one of the most common reproductive system disorders in women, is a clinical condition in which chronic inflammatory parameters increase. In this study, we aimed to evaluate the epi...
Evaluation of the Relationship Between Thyroid Dysfunction and Menstrual Migraine in Adult Females
Aim: Menstrual migraine (MM) is a condition linked to sudden estrogen withdrawal, however, changes in vascular system and neurotransmitters and several hormones are thought to be the underlying causes. Thyroid function a...
Non-appendicitis Diagnoses in Patients Operated Due to Acute Appendicitis
Aim: The aim of the present study was to evaluate patients who were operated due to acute appendicitis and who were later determined to have non-appendicitis pathologies. Methods: The demographic characteristics, histop...
Comparison of Nutritional Screening Tools in Patients Undergoing Surgery for Gastric Cancer
Aim: Nutritional screening tools are mainly used to identify patients at risk of malnutrition. We aimed to compare commonly used nutritional tools in assessing the nutritional status of patients undergoing surgery for ga...