Cytoreductive Surgery and Hyperthermic İntraperitoneal Chemoterapy for Advance Gastric Cancer Associated Peritoneal Carcinomatosis Single Centre Unit for 10 Consecutive Patients
Journal Title: The Medical Bulletin of Haseki - Year 2019, Vol 57, Issue 3
Abstract
Aim: Hyperthermic intraperitoneal chemotherapy with cytoreductive surgery has a positive effect on survival in advanced abdominal cancers. We aimed to present our experience with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in gastric cancer patients with peritoneal carcinomatosis and a review of the literature. Methods: Ten patients (seven male, three female) who were diagnosed with gastric cancer between June 2017 and November 2018 were included in the study. Data on demographic characteristics, short-term follow-up results, surgical findings, peritoneal carcinomatosis index score, completeness of cytoreduction score, and morbidity and mortality rates were retrospectively analyzed. Results: The mean age of the patients was 60.3 years. The mean follow-up period was six months (1-15 months). One patient developed an anastomotic leak. In the other nine cases, there was no morbidity leading to mortality. Conclusion: While gastric cancer with peritoneal carcinomatos has a poor survival, less than six months with non-operative approach, treatment with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy offers better outcomes and overall survival. Our first results in our study with a limited number of patients are satisfactory and multicentric randomized studies are needed on this subject.
Authors and Affiliations
Özgül Düzgün, Sema Yüksekdağ, Murat Kalın, Şenol Çomoğlu, Semra Yanık, Ömer Faruk Özkan, Neşet Köksal
Keywords
Related Articles
- EP ID EP50767
- DOI 10.4274/haseki.galenos.2019.4997
- Views 260
- Downloads 0
Relationship Between Frailty and Medicine Use and Polypharmacy in People Over Sixty-five Years of Age
Aim: Frailty has become an important health issue in recent years. The aim of this study was to investigate the relationship between frailty and medicine use and polypharmacy in people over 65 years of age. Methods: Pat...
Impact of Admission, Fasting Glucose and HbA1c Levels on in-stent Restenosis in The Patients Treated with Primary Percutaneous Coronary Intervention in 5-Year Follow-up
Aim: Despite advances in-stent technology, in-stent restenosis (ISR) is still a major problem following percutaneous coronary intervention (PCI) and its reasons have not been fully revealed. In the presented study, we in...
A Survey Analyzing Reflections of COVID-19 on Patients and Their Relatives
Aim: In this study, we aimed to analyze the level of knowledge about Coronavirus disease-2019 (COVID-19) in patients and their relatives presented to the emergency department. Methods: In this study, a 25-item questionn...
Safety of Microstream Capnography Monitoring in Patients Under Sedation for Colonoscopy
Aim: "The purpose of this study was to investigate the effectiveness of micro stream capnography in early recognition of adverse events during sedation for colonoscopy. Methods: This prospective randomized study was per...
The Role of Interleukin-4 VNTR Polymorphism in Dysmenorrhea Development
Aim: Primary dysmenorrhea (PD) is among the most common gynecological diseases in young women presenting to emergency department. It has been shown that cytokines played roles in PD pathogenesis. Interleukin-4 (IL-4), a...