Cytoreductive Surgery and Hyperthermic İntraperitoneal Chemoterapy for Advance Gastric Cancer Associated Peritoneal Carcinomatosis Single Centre Unit for 10 Consecutive Patients
Journal Title: The Medical Bulletin of Haseki - Year 2019, Vol 57, Issue 3
Abstract
Aim: Hyperthermic intraperitoneal chemotherapy with cytoreductive surgery has a positive effect on survival in advanced abdominal cancers. We aimed to present our experience with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in gastric cancer patients with peritoneal carcinomatosis and a review of the literature. Methods: Ten patients (seven male, three female) who were diagnosed with gastric cancer between June 2017 and November 2018 were included in the study. Data on demographic characteristics, short-term follow-up results, surgical findings, peritoneal carcinomatosis index score, completeness of cytoreduction score, and morbidity and mortality rates were retrospectively analyzed. Results: The mean age of the patients was 60.3 years. The mean follow-up period was six months (1-15 months). One patient developed an anastomotic leak. In the other nine cases, there was no morbidity leading to mortality. Conclusion: While gastric cancer with peritoneal carcinomatos has a poor survival, less than six months with non-operative approach, treatment with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy offers better outcomes and overall survival. Our first results in our study with a limited number of patients are satisfactory and multicentric randomized studies are needed on this subject.
Authors and Affiliations
Özgül Düzgün, Sema Yüksekdağ, Murat Kalın, Şenol Çomoğlu, Semra Yanık, Ömer Faruk Özkan, Neşet Köksal
Keywords
Related Articles
- EP ID EP50767
- DOI 10.4274/haseki.galenos.2019.4997
- Views 263
- Downloads 0
Cytomegalovirus Duodenitis in a Renal Transplant Patient Presenting with Signs of Gastrointestinal Bleeding: A Case Report
Cytomegalovirus (CMV) is a common virus that causes opportunistic infections in many organ systems in immunocompromised patients. CMV infections are also an important problem in renal transplant patients. CMV infection o...
The Role of Whole-blood Parameters in Predicting the Severity of Acute Rheumatic Carditis in Children
Aim: Acute rheumatic fever (ARF) is the most common cause of acquired heart disease especially in developing countries. This study is intended to evaluate the relationship between severity of cardiac involvement and hema...
The Difference of Thyroid Cancer in Hyperactive Adenoma and Hyperthyroidism in Endemic Areas
Aim: In recent years, dramatic changes in treatment approaches and conflicting publications on thyroid cancer have been reported from endemic regions. The probability of cancer has increased in endemic areas especially i...
Relationship of Gender and Serum Calcium and/or Phosphorus Levels on Admission with the Etiology and Early Prognosis of Hypercalcemia
Aim: Hypercalcemia (HCM) is a common clinical problem characterized by a serum corrected calcium (cCa) level of >10.7 mg/dL. Primary hyperparathyroidism and malignancy are mostly (90%) involved in the etiology. In this s...
Correlation of the Severity of Carotid Artery Stenosis Identified by 64 Detected CT using ‘‘CC’’ Method with Color Doppler Ultrasound Findings
Aim: The aim of this study was to investigate the correlation between the severity of carotid stenosis determined with 64-multidetector row computed tomographic angiography (CTA) (64-MDCTA) using the ‘‘common carotid’’ (...