CYTOTOXIC ACTIVITY OF AVOCADO SEEDS EXTRACTS (Persea americana MILL.) ON T47D CELL LINES
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2014, Vol 5, Issue 7
Abstract
Avocado (Persea americana Mill.) is a widely grown plant that had been studied for several activities such as antioxidant and chemopreventive. The aims of this study were to analyze the secondary metabolite compounds contained in avocado seeds and to determine cytotoxic effect from aqueous and ethanolic extracts of avocado seeds against T47D breast cancer cell lines. IC50 value obtained by using MTT assay on aqueous extract, ethanolic extract, and doxorubicin hydrochloride were 560,2 µg/mL, 107,15 µg/mL and 0,26 µg/mL, respectively. Phytochemical screening test had detected the alkaloids, glycosides, phenols, and saponins as chemical groups in avocado seeds extracts.
Authors and Affiliations
Elenora Kristanty, Junie Suriawati, Joko Sulistiyo
Keywords
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- EP ID EP142291
- DOI 10.7897/2230-8407.0507113
- Views 113
- Downloads 0
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