Cytotoxicity of toothpastes used for gum health
Journal Title: International Journal of Medical Science and Dental Research - Year 2019, Vol 2, Issue 1
Abstract
Objective:The aim of this study was to evaluate the cytotoxic effects of 4 different toothpaste on the L929 mouse fibroblast cells.Materials and Methods: Cytotoxicity of Colgate Total Pro Gum Health, Ipana Pro Expert Clinic Line Gum Protection, Paradontax Compelete Protection and Paradontax Extra Fresh toothpastes evaluated by XTT assay on L929 cells Results: Different degrees of cytotoxicity were observed in toothpastes. Mean survival rate of L929 cells exposed to Colgate Pro Gum Health in wells were 57,25%, 56,71% for Ipana Pro Expert Clinic Line Gum Protection, 45,05% for Paradontax Complete Protection and 37,49% for Paradontax Extra Fresh. Coclusion:Toothpastes, marketed for gum health are cytotoxic. Paradontax Complete Protection and Paradontax Extra Fresh more cytotoxic than Colgate Total Pro Gum Health and Ipana Pro Expert Clinic Line Gum Protection to L929 cells. We recommend manufacturers to review the contents of their toothpastes.
Authors and Affiliations
H. Esra Ülker, A. C. Tutku Çelik, Türkay Kölüş
Keywords
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