Czerniaki złośliwe regionu głowy i szyi w materiale Kliniki Chirurgii Onkologicznej i Rekonstrukcyjnej Centrum Onkologii IMSC w Gliwicach
Journal Title: Otolaryngologia Polska - Year 2010, Vol 64, Issue 7
Abstract
Introduction: About 25% of melanomas are localized in head and neck skin, and this particular localization is most diffi cult to treat, and the prognosis is less favorable. The depth of melanoma infi ltration (Clark and Breslau grade) into the skin is the main factor of local advancement of the disease. Surgical treatment is an essential therapeutic modality in patients with melanoma. Aim: The aim of this study was to evaluate results of our surgical treatment of melanomas in head and neck localisation, treated from 1997 to 2007 in Department of Oncological and Reconstructive Surgery in Center of Oncology IMSC in Gliwice. Material: We analysed group of 47 patients (aged 26 to 75 years, mean 49), treated by surgical excision of malignant melanoma in the head and neck region. Most of the patiens required to use free fl aps or skin graft technique to close posexcisional defect, on basis of clinical considerations. Results: The 5-year total survival for all patients was 62% and were dependent on depht of melanoma infi ltration and regional lymph node metastasis. The signifi cant prognostic factors were: localization of primary focus, local progression of disease, free microscopical excision margins sex and age. Conclusions: Prognosis in the patients with melanoma of the head and neck is unreliable and dependent on local advancement of disease and localization of primary focus. Surgical treatment is an essential therapeutic modality in patients with melanoma. Adiuvant radiotherapy after surgical treatment of melanoma of the head and neck is intended for the patiens with high risk of local or regional recurence of disease.<br/><br/>
Authors and Affiliations
Łukasz Krakowczyk, Adam Maciejewski, Maciek Grajek, Cezary Szymczyk, Janusz Wierzgoń, Piotr Jędrzejewski, Stanisław Półtorak
Keywords
Related Articles
- EP ID EP345876
- DOI -
- Views 80
- Downloads 0
Włókniak chrzęstno-śluzowaty przegrody nosa
Introduction: Chodromyxoid fibroma (CMF) is a rare benign tumor, typically occurring in the metaphysis of long bones. Involvement of craniofacial bones is extremely unusual. The histologic diagnosis of this tumor is diff...
Aktualny pogląd na gruźlicze zapalenie węzłów chłonnych w kontekście epidemii HIV jak również wielolekoopornej i rozlegle wielolekoopornej gruźlicy
Całkowicie wszczepialny implant ucha środkowego — wskazania, technika chirurgiczna i wyniki pierwszej operacji
SUMMARY Akr The aim of this study is to present indications, surgical technique and first results of fully implantable middle ear implant (Otologics Carina), first time in Polish clinical practice. A/121-ari21 nfi małhrt...
Mutacje mitochondrialnego DNA w rozwoju nowotworów głowy i szyi
Data reported until today suggested a pivotal role of nuclear DNA mutations in the process of carcinogenesis. Recently more and more authors claim that disruption of mitochondrial DNA should not be excluded from this ana...
Diagnostyka i terapia nowotworów złośliwych głowy i szyi u ciężarnych
SUMMARY The coincidence of malignant disease during pregnancy is uncommon. The incidence of cancer in pregnancy has increased, due to the tendency to post-pone childbirth to an older age. Cancer complicates approximately...