Dapsone hypersensitivity syndrome - A case report
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2018, Vol 8, Issue 4
Abstract
Dapsone is widely used for the treatment of leprosy and other immunological and inflammatory dermatological conditions such as dermatitis herpetiformis, vesiculobullous dermatoses, and pustular psoriasis. Dapsone hypersensitivity syndrome (DHS) is a rare reaction associated with fever, skin eruptions, and internal organs involvement. We report a case of DHS who presented with fever, productive cough, dyspnea, skin rashes, and jaundice. Leukocytosis, eosinophilia, and altered liver enzymes were observed in laboratory investigations and patient improved with conservative management.
Authors and Affiliations
Selvalaxmi Gnanasegaran, Mangaiarkkarasi Adhimoolam, Srija Gopal
Keywords
Related Articles
- EP ID EP487845
- DOI 10.5455/njppp.2017.7.1042308112017
- Views 74
- Downloads 0
Pattern of drug usage among medical students in Tumkur, Karnataka
Background: Scheduled drugs are also purchased without prescriptions, which is a cause for concern. Educational status is an important determinant of self-medication. Student drug use surveys provide an essential source...
Dapsone-induced methemoglobinemia in immune thrombocytopenia: A case report
ITP is a bleeding disorder which is not associated by a systemic disease caused by low platelet count or thrombocytes. However, use of dapsone is limited by adverse effects such as methemoglobinemia, reticulocyte increas...
Fluoroquinolones in India—Are we prescribing it right: A cost variation study
Background: Quinolones are the fastest growing antibacterial agents worldwide as they are being used in both the hospitals and community practices to treat infections. Ciprofloxacin and levofloxacin dominate the m...
Effect of participatory care on the satisfaction of parents of children admitted to the children’s wards: Clinical trial study
Background: Family participation in the care and treatment of a patient child causes a sense of safety and satisfaction in the child and his or her family. One of the most important duties of nurses, along with providing...
Immediate effect of contract-relax antagonist-contract method on iliopsoas muscle and hamstring muscle stretching in chronic non-specific low back pain
Background: Low back pain (LBP) is a common musculoskeletal problem in recent days, and 85% of LBP is NSLBP. Studies have shown that psoas syndrome can be the cause of pain in lumbosacral region in a clinical scenario. A...