Dapsone Induced Hypersensitivity Syndrome
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2018, Vol 13, Issue 1
Abstract
‘Dapsone Hypersensitivity Syndrome’ (DHS) is one of the most serious adverse reaction of Dapsone. DHS is characterized by exfoliative dermatitis, fever, internal organ involvement (Lungs, Liver, Spleen, and Kidney). The recorded incidence of DHS was 1.3 % among leprosy patients in India. The current case report is of 36 years old female patient who presented with high grade fever, exfoliative dermatitis and hepato-renal dysfunction. The patient was successfully managed by immediate withdrawal of Dapsone and administration of corticosteroids.
Authors and Affiliations
Punam R. Kela, Shruti M. Pachpohar
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