Demyelinating disease can hide HIV-infection Case report
Journal Title: Туберкульоз, легеневі хвороби, ВІЛ-інфекція - Year 2018, Vol 0, Issue 4
Abstract
A significant part of patients with HIV / AIDS develops damage to the nervous system. There are also cases where opportunistic infections of the nervous system, especially herpes viral origin, can hide the underlying disease, making it difficult diagnosis. Here, we report a case of a 41-years-old female presented to The Cеntег of Infectious disorders of the Nervous System (Kyiv, Ukraine) in August, 2018 after developing acute fever following by a left side hemiparesis, violation of coordination. Previously, a demyelinating disease was suspected. Tuberculosis and HIV denied. Her physical examination showed tremor in her hands during a Barre-probe. She performed the coordination tests with intent, staggering in the Romberg pose. A small brain lesion was revealed at MRI. Antibodies to HSV1/2, CMV, Tox. gondii were found in the CSF and blood. Blood PCR was reported to be positive for DNA EBV, and RNA HCV. A rapid HIV test was negative. A repeated blood test performed 10 days after admission showed low level of CD4+ T cells (36 cells/1 μl), and HIV RNA (850.104 cp/ml). HIV antibodies were also revealed. As a result, patient was transferred to a specialized department for further treatment. Conclusions. Considering high clinical polymorphism of HIV/AIDS, physicians of all specialties should be alert for the possible neurologic manifestations of this disease to timely examine patients.
Authors and Affiliations
P. A. Dyachenko
Keywords
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- EP ID EP462330
- DOI 10.30978/TB2018-4-73
- Views 95
- Downloads 0
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