Peculiarity diagnosis of tuberculosis in HIV-infected
Journal Title: Туберкульоз, легеневі хвороби, ВІЛ-інфекція - Year 2018, Vol 0, Issue 2
Abstract
Objective — to analyze the spectrum and frequency of detection extrapulmonary clinical forms of tuberculosis and determinate plans of diagnosis among patients with HIV infection. Materials and methods. 55 cases of tuberculosis in HIVinfected, which examined by additional methods: CT, MRI, Ultrasound. Results and discussion. Isolated pulmonary tuberculosis observes only in 13 (23.6 %). Many of patients with extrapulmonary tuberculosis without lung damage in — 1 (1.8 %), 34 (61.8 %) have combined forms of tuberculosis (lung + extrapulmonary localization), generalized forms with multiple localizations 7 (12.7 %). Out of major extrapulmonary localizations is most prevalent the tuberculosis of the lymphatic system (40.0 %), pleura (18.2 %) and central nervous system (7.3 %). Bacteriaexcretion has detected in 28 (55.9 %) patients. The chemoresistant forms of tuberculosis diagnoses in 19 patients (34.5 %), including multidrugresistant forms with RRTB in 18 (32.7 %), sensitive to preparations of the form of tuberculosis in 32 (58.2 %) patients. All patients have hospitalized with tuberculosis of the lungs. Of the patients surveyed in 74.5 % of CD4 < 200 cells/mm3, 49 % of them have chronic hepatitis B and C. The modern patients with HIV/TB coinfection are patients with tuberculosis and multiple localizations in combination with chronic hepatitis and other opportunistic illnesses against a background of an immunosuppression with CD4 less 200 cells/mm3. Conclusions. The results of the examination testify to the necessity of compulsory CT chest cavity and ultrasound examination of the abdominal cavity in the diagnosis of tuberculosis/HIVinfected patients with substantial immunosuppression.
Authors and Affiliations
O. D. Nykolaeva
Keywords
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