DENGUE FEVER INFECTION EVALUATION OF ANTI-DENGUE IGM OR IGG USING NUMEROUS RAPID DIAGNOSTIC TESTS (RDTS)
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2018, Vol 5, Issue 12
Abstract
Dengue fever (DV) is a mosquito-borne tropical disease caused by one of four dengue viruses. It is necessary to test the commercial rapid diagnostic kits for DV infection. In this study, we evaluated the accuracy and precision of DV relative to the manufacturer’s specifications at General Hospital Kulala Lumpur, KL, Malaysia. Three commercially available dengue rapid diagnostic tests (RDT) kits were evaluated. We used Asan Easy Test, BIOLINE Dengue Duo, and PanBio as the RDT in the study. Specificity of Asan Easy Test was100.0% (75/75) for IgM and its sensitivity was 64.6% (73/113). The detection of IgG was same trend. Specificity of Asan EasyTest was100.0% (75/75) for IgG and its sensitivity was 31.6% (18/57). Specificity of SD BioLine was100.0% (75/75) for IgM and its sensitivity was 53.7% (50/113). Specificity of SD BioLine was100.0% (75/75) for IgG and its sensitivity was 21.0% (12/57). Specificity of PanBio was100.0% (75/75) for IgM and its sensitivity was 41.5% (47/113). Specificity of PanBio was100.0% (75/75) for IgG and its sensitivity was 22.9% (13/57). Asan EasyTest had greater overall sensitivity than SD BioLine and PanBio.
Authors and Affiliations
Yong Lim
Keywords
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