ALTERNATIVE MEDICINE: PLA2 EFFECT FROM DABOIA SP. VENOM IN CANCER THERAPY
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2018, Vol 5, Issue 10
Abstract
PLA2 is a major enzymatic of Daboia species venom which has broad pharmaceutical effects. There are many reports on PLA2 against various cancer cells from a variety of animal venoms. Nevertheless, there was a few publishes from Daboia species venom on cancer. Here, we accumulated the reports on hydrolysis function of PLA2s from snake venom on cancer cells especially from Daboia siamensis and Daboia russelii russelii. In addition, it also showed the effects from less to mild on normal cells. Overall, these findings have proved that PLA2 property could be potent various anticancer agents. Further studies are required to elucidate the mechanism of this enzyme which induced anticancer activities. However, the efforts to better integrate research and innovation cooperation especially researchers in the housing area of this snake should look forward to the future.
Authors and Affiliations
Suchitra Khunsap
Keywords
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