Dengue in Pregnancy
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 1
Abstract
Background: Dengue is the most rapidly spreading mosquito borne viral disease in the world. There is an increase in incidence of dengue in adult population in South Asian countries in recent years. Objective: To study the pattern of dengue in pregnancy and the impact of dengue on the natural course of pregnancy. Materials & Methods: All pregnant patients admitted with fever and features suggestive of dengue infection were included in the study. The demographic data, clinical features, hematological and biochemical parameters were collected. Serological testing for dengue virus specific antigen and antibody was done for the diagnosis of dengue fever. The World Health Organization classification and case definitions 2009 was used to categorize the dengue patients. The variable pattern of the disease and the effect of dengue infection on the natural course and outcome of pregnancy and labour was studied. Results: Of the 49 pregnant patients admitted with suspected dengue infection, 16 were diagnosed serologically with dengue. Of these 6 (37.59%) had primary dengue and 10 (62.5%) had secondary dengue infection. Eight patients were diagnosed with dengue in the second trimester. Number of patients who had dengue ± warning signs and severe dengue were 14 (87.5%) and 02 (12.5%) respectively. Skin rashes were seen in 09 (56.2%) patients, vomiting in 4 (25%) patients. Severe thrombocytopenia was seen in 2 (12.5%). Preterm labour was seen in 8 (50.0%) patients. Conclusion: This study highlights the clinical pattern and the natural course of dengue in pregnancy. The clinical presentation of dengue in pregnancy is almost similar to dengue in non pregnant adults. There is increased association of dengue with preterm delivery and low birth weight. The treatment of dengue in pregnancy is mainly conservative as in non pregnant adults
Authors and Affiliations
Dr. Neelakandan Ramya
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