Detection, genotyping and phylogenesis of human papillomavirus (HPV) and Epstein-Barr virus (EBV) in patients with lung cancer
Journal Title: Current Issues in Pharmacy and Medical Sciences - Year 2012, Vol 25, Issue 2
Abstract
The lung cancer is one of the most common cancers in humans. It is now believed, that the most common cause of this disease is smoking, nevertheless also research on oncogenic viruses participating in the development of this type of tumor confirms that. Human papillomavirus (HPV) and Epstein-Barr virus (EBV) are the etiologic agents of several types of cancer. The dynamic development of molecular biology techniques and bioinformatics allows for the genotyping of microorganisms in a more accurate and reliable way. In this paper, we carried out the detection and genotyping of HPV and EBV in fragments of fresh tissue obtained from patients with the lung cancer. In addition, typing results are presented graphically in phylogenetic trees.
Authors and Affiliations
Łukasz Podsiadło, Sławomir Mańdziuk, Małgorzata Polz-Dacewicz, Agnieszka Stec, Jarosław Buczkowski
Keywords
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