DETECTION OF ENZYMES DEHYDROGENASES AND PROTEASES IN BRUGIA MALAYI FILARIAL PARASITES
Journal Title: Indian Journal of Clinical Biochemistry - Year 2006, Vol 21, Issue 1
Abstract
Lymphatic filariasis caused mainly by infection from W. bancrofti and B. malayi remains a major cause of clinical morbidity in tropical and subtropical countries. Analysis of B.malayi mf, infective larval and adult worm lysates for the activity of enzymes led to the demonstration of activities of three key enzymes of carbohydrate metabolism viz., Malate dehydrogenase (MDH), Malic enzyme (ME) and Glucose-6-phosphate dehydrogenase (G6PDH) in all the three stages of the parasite. The specific activity of all the three dehydrogenases was significantly high in mf lysate compared to their activity in lysates of the other two stages (P
Authors and Affiliations
Y. P. Bhandary, K. N. Krithika, Sandeep Kulkarni, M. V. R. Reddy, B. C. Harinath*
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