Determination of levels of haematocrit and erythropoietin in persons living with HIV in Umuahia
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH IN MEDICAL SCIENCES - Year 2016, Vol 2, Issue 6
Abstract
The study was done to determine the levels of haematocrit and erythropoietin in persons living with HIV in Umuahia. A total number of one hundred and ten (110) subjects were recruited for the study. The subjects were divided into two groups; the first group consists of HIV positive subjects (test group) and the second group consists of HIV negative subjects (control group).Serum sample was used for the estimation of erythropoietin. Sandwich ELISA method was used to estimate erythropoietin e estimation of haemoglobin. while EDTA anticoagulated blood was used for test . The results were analysed using t-test with level of significance set at P<0.05.The results showed significant decrease (p<0.05) in both erythropoietin and haematocrit level of the HIV patients (6.21±3.46 Mu/Ml,31.26±3.52%) compared to HIV negative subjects (13.63±5.19 Mu/Ml,42.93±7.16%) respectively. The study showed that there was derangement in the kidney of the HIV patients which decreased erythropoietin synthesis and release and induced anaemia in the patients.
Authors and Affiliations
*Obeagu, Emmanuel Ifeanyi1 , Obeagu, Getrude, Uzoma2 , Nwandikor, Uzoije, U. 1 , Onyenweaku, Florence C. 1
Keywords
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