DEVELOPMENT AND EVALUATION OF ALBENDAZOLE MICROCAPSULE FOR COLONIC DRUG DELIVERY SYSTEM
Journal Title: Universal Journal of Pharmaceutical Research - Year 2017, Vol 2, Issue 2
Abstract
At present scenario colon specific drug delivery has gained increased importance. Colon drug delivery system not only used for the treatment of local diseases, associated with the colon but also it is a potential site for systemic delivery of therapeutic drug. Albendazole is a benzimidazole carbamate broad spectrum oral anthelmetic drug. It is poorly water soluble and it undergoes extensive metabolism in the intestine and liver. Different batches of Albendazole microcapsules were prepared using different concentration of polymers like Eudragit RS-100, chitosan, HPMC. The microcapsules were then evaluated for micromeritic properties, percentage yield, incorporation efficiency, drug content. In vitro dissolution profile of each formulation was determined by employing USP XXIII rotating basket method.
Authors and Affiliations
Onyeka Ifeanyi Peter, Ukwe Chioma Ifeoma
Keywords
Related Articles
- EP ID EP36382
- DOI https://doi.org/10.22270/ujpr.v2i2.R2
- Views 357
- Downloads 0
IN VITRO ANTI-LEISHMANIAL ACTIVITY AGAINST CUTANEOUS LEISHMANIA PARASITES AND PRELIMINARY PHYTOCHEMICAL ANALYSIS OF FOUR YEMENI MEDICINAL PLANTS
Cutaneous leishmaniasis is one form of leishmaniasis that chiefly infected the poor sections of the society. The prototypical therapeutic interventions in vogue are handicapped due to toxicity and an alarming increase in...
FABRICATION AND EVALUATION OF HERBAL OINTMENT FORMULATIONS OF MORINGA OLIFERA FOR TOPICAL DELIVERY
Traditional medicine is an important source of potentially useful new compounds for the development of chemotherapeutic agents. Moringa oleifera Lam. is a multipurpose and exceptionally nutritious vegetable tree with a v...
Editorial.
It is great honor and privilege for me to be appointed as Member - Editorial Board, Universal Journal of Pharmaceutical Research (UJPR). My heartiest salutations to Prof. Dr. Kapil Kumar, Editor-in-Chief and the other bo...
Editorial Message
It is a great honor for me to join the Universal Journal of Pharmaceutical Research (UJPR) as a member in the Editorial Board team. I would like to extremely congratulate all the UJPR team for completing approx. two succ...
THE EFFECT OF HOSPITAL MANAGERS' SUCCESSION PLANNING ON ORGANIZATIONAL PERFORMANCE: A CASE STUDY OF SHOUSHTARI MATERNITY HOSPITAL IN SHIRAZ IN 2017
Widespread and rapid changes that have been created in current organizations, have led to feel lack of managers with skill for key jobs of organization and hence about the importance of succession planning in organizatio...