Development and Validation of UV Spectrophotometric Method for determination of Bisacodyl in Suppositories
Journal Title: International Journal of PharmTech Research - Year 2011, Vol 3, Issue 1
Abstract
A simple, precise, accurate, rapid and economical method for determination of bisacodyl has been developed using UV spectrophotometry. The determination was carried out at absorption maxima of 264nm using methanol and 1M glacial acetic acid as solvents. The analytical method was validated for linearity, accuracy, robustness and specificity and system suitability for both the solvents namely methanol and 1M glacial acetic acid. The method used for determination of bisacodyl using solvents (methanol and 1M glacial acetic acid) complies with the acceptance criteria set for the aforementioned analytical parameters. Hence, the current method stands validated. The currently developed method can be used for routine QC quantitation of bisacodyl in Suppositories
Authors and Affiliations
ELVIS MARTIS, DEEPALI GANGRADE
Keywords
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Development and Validation of UV Spectrophotometric Method for determination of Bisacodyl in Suppositories
A simple, precise, accurate, rapid and economical method for determination of bisacodyl has been developed using UV spectrophotometry. The determination was carried out at absorption maxima of 264nm using methanol and 1...
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