Screening of Madhuca indica for Antidiabetic Activity in Streptozotocin and Streptozotocin – Nicotinamide induced Diabetic Rats
Journal Title: International Journal of PharmTech Research - Year 2011, Vol 3, Issue 2
Abstract
Diabetes is a chronic metabolic disorder characterized by hyperglycemia and polyurea and this is the leading disease in the world causing morbidity. Many allopathic medicines are available to treat diabetes, but treatment associates with many side effects which were compensated by replacing allopathic medicine with natural drugs. Many natural drugs shown significant antidiabetic activity but all those natural drugs are not commonly available which provoked us to initiate the present study of evaluation of Antidiabetic activity of Madhuca indica. In this present study we extracted Madhuca indica by using different solvents viz. methanol, Petroleum ether and water. Among these extracts Methanolic extract of Madhuca indica has shown significant anti diabetic activity against streptozotocin and streptozotocin – nicotinamide induced diabetic models in wistar rats.
Authors and Affiliations
K Pavan Kumar , G Vidyasagar , D Ramakrishna , Madhusudhana Reddy I, VSSS Gupta Atyam, Ch Sarva Raidu
Keywords
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- EP ID EP86921
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Screening of Madhuca indica for Antidiabetic Activity in Streptozotocin and Streptozotocin – Nicotinamide induced Diabetic Rats
Diabetes is a chronic metabolic disorder characterized by hyperglycemia and polyurea and this is the leading disease in the world causing morbidity. Many allopathic medicines are available to treat diabetes, but treatme...