Development of Fast Disintegration Tablets As Oral Drug Delivery System-A Review
Journal Title: Indian Journal of Pharmaceutical and Biological Research - Year 2013, Vol 1, Issue 3
Abstract
Fast disintegrating tablets (FDTs) have received increasing demand from the last few years and the field has become a rapidly growing field in the pharmaceutical industry. Fast disintegrating tablets (FDTs) are those solid doses form which when put on the tongue gets rapidly dissolved, releasing the drug within a few second without need of water. The development of FDTs have been formulated for paediatric, geriatric and bedridden patients and for active patients who are busy and travelling and may not have access to water. Such formulation provide an opportunity for product line extension in the many elderly persons will have difficulties in taking conventional oral doses forms (viz, solution suspensions tablet and capsules) because of hand tremors and dysphagia. This article focused on ideal requirements, need for development of FDTs, challenges in formulations, suitability of drug candidates superdisintegrants employed, various technologies developed for FDTs. Evaluation methods, and various marketed products.
Authors and Affiliations
Chiman Beri| LR Institute of Pharmacy, Jabli Kyar, Solan (H.P.), India, Isha Sacher| LR Institute of Pharmacy, Jabli Kyar, Solan (H.P.), India
Keywords
Related Articles
- EP ID EP13649
- DOI -
- Views 367
- Downloads 19
Development and Validation of a HPLC-UV Method with Pre-column Derivatization for Determination of Cinnabar in Jufang Zhibao Pills
In this work, a reliable and accurate high-performance liquid chromatography method with pre-column derivatization was established and validated for determination of cinnabar in Jufang Zhibao pills. Scanning electron mic...
Evaluation of Phytochemical Constituents of Indian Medicinal Plant Hydnocarpus alpina WIGHT
Hydnocarpus alpina WIGHT. is a evergreen forest plant. It is an endemic plant to western ghats of India. Several local names are available based on distribution among the state in india that is Torathi (kanada), Maravet...
Development of Anti-diabetic Niosomes Formulation Containing Metformin and Gliclazide
Metformin/Gliclazide niosomes were formulated with span 60 by ether injection method. Three batches MG1-MG3 were prepared in order to study influence of drug polymer ratio on the niosomes formation and in vitro drug re...
A Randomised Controlled Trial Comparing Intravaginal Misoprostol and Intracervical Dinoprostone in Pre Induction Cervical Ripening
Objective: To compare the efficacy and safety of intravaginal misoprostol with intracervical dinoprostone for preinduction cervical ripening. Material &Methods: It was a randomized controlled trial conducted at departme...
Comparative Evaluation of semisolid bases for transdermal use of Ketorolac tromethamine
Ketorolac tromethamine (KT) is a non-steroidal anti-inflammatory drug that belongs to class of heteroacetyl derivatives. An attempt has been made to make use of ointments, creams and gels as suitable vehicles for KT, w...