DIABETES: QUANTUM ANALYSIS OF THE INTERACTIONS OF CARNOSINE AND OTHER DIPEPTIDES VS. GLUCOSE
Journal Title: World Journal of Pharmaceutical Research - Year 2018, Vol 7, Issue 10
Abstract
The treatments with carnosine and other peptides have revolutionized science in recent years. Researchers show that treatment with carnosine improves glucose (GLU) metabolism, albuminuria, and pathology. The objective of this research was to analyze the chemical-quantum interactions of GLU with pure amino acids (AAs) and dipeptides. The hyperchem simulator was used to perform quantum calculations. These calculations are based on the Electron Transfer Coefficient (ETC). The following discoveries were made: the GLU is very aggressive and can attack any AA in its pure state. GLU also attacks dipeptides, polypeptides, and biological tissue. Carnosine has an ETC = 33.824, and there are other dipeptides with lower ETC. All dipeptides of Histidine (His) keep their ETC value = 33.824 constant, which is the ETC value of carnosine. It concluded that all dipeptides of His must have similar behavior to carnosine. Laboratory studies of these His dipeptides are suggested in order to control blood GLU and nephropathies for diabetic patients.
Authors and Affiliations
Dr. Manuel Gonzalez- Perez
Keywords
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