DIAGNOSIS OF ACUTE LEUKEMIA BY FLOWCYTOMETRY IN POPULATION OF TRIPURA, NORTH-EAST INDIA
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2014, Vol 1, Issue 10
Abstract
The aim of this study was to diagnose acute leukemia in the population of Tripura using 3-lasers 7-color Flowcytometer. Immunophenotyping was done on peripheral blood samples of acute leukemia cases, by using 2-tube basic AML antibody panel. Samples collected from Regional Cancer Centre, Agartala included in this study 15 Acute Leukemia cases, reported during 2013 & 2014. Among them, 4 were ALL and 11 were AML cases. Out of 15 cases, 12 were adults (9 men and 3 women ranging from 17 to 77 years of age) and 3 were from pediatric patients. A strong correlation (r=0.92) is obtained between the blast cell count by microscopy &flowcytometry. Moreover, this Immunophenotyping procedure on peripheral blood samples also allowed an efficient discrimination between the various cell lineages and facilitated the accurate leukemic blast cell percentage.
Authors and Affiliations
Arup Bhaumik, Shikha Das, Sandeep Roy Sarkar, Payel Chakraborty, Biswajit Chowdhury
Keywords
Related Articles
- EP ID EP225760
- DOI 10.18410/jebmh/2014/196
- Views 87
- Downloads 0
ANATOMICAL VARIATIONS OF RENAL ARTERY AND ITS SURGICAL CORRELATIONS: A CADAVERIC STUDY
BACKGROUND Kidneys are retroperitoneal organs normally supplied by the paired renal arteries. Each kidney is supplied by a single renal artery which arises as a lateral branch of abdominal aorta, between the levels of L1...
MISOPROSTOL FOR THE PREVENTION OF POST-PARTUM HAEMORRHAGE: A RANDOMIZED CONTROLLED TRIAL
BACKGROUND The leading causes of pregnancy-related deaths are haemorrhage, embolism and hypertensive disorders of pregnancy. Postpartum haemorrhage is a major preventable cause of maternal morbidity and mortality in deve...
SONOGRAPHIC EVALUATION OF ABDOMINAL HYDATID DISEASE
BACKGROUND Hydatid disease is one of the most common surgical conditions in Kurnool district of Andhra Pradesh. Ultrasonography is the initial investigation of choice in detecting and characterizing the disease. Ultrasou...
MORPHOMETRIC STUDY OF CALCANEOFIBULAR LIGAMENT OF ANKLE
The ligaments of the ankle joint are medial and lateral collateral ligaments. Medial deltoid ligament has superficial and deep components. Lateral collateral ligament has Anterior Talofibular (ATFL), Calcaneofibular (CFL...
COMPARISON OF ROCURONIUM BROMIDE AND SUCCINYLCHOLINE CHLORIDE FOR USE DURING RAPID SEQUENCE INTUBATION IN ADULTS
The goal of rapid sequence intubation is to secure the patients airway smoothly and quickly, minimizing the chances of regurgitation and aspiration of gastric contents. Traditionally succinylcholine chloride has been the...