Diagnosis of peripheral artery disease in Saudi Population - CTA and MRA Based Study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 11
Abstract
The current study highlight the main findings in lower limb arteries diagnosed by Computerized Tomography Angiography(CTA) and Magnetic Resonance Angiography (MRA) done for Saudi Arabia population whom were smokers, hypertensive and diabetic. As well to evaluate which arteries were better to be diagnosed by CTA and which was better be diagnosed by MRA. Next, to review the properties of different visualization techniques for extracting the relevant findings finally, discuss the practical application of CT and MR angiography within the context of various conditions. 100 consecutive patients in both genders were enrolled. Their main pertinent medical history included smokers (n = 30), diabetics (n = 45) and hypertensive (n = 25). The main symptoms of the patients were limb pain and claudication, with an average duration of 11.5 months. All were underwent MRA and CTA under the standard protocol of examinations. For the whole sample ,arteries above the femur were evaluated by CTA and the results showed that stenosis was found in common iliac, external iliac, internal iliac, femoral, and femoral profound artery, MRA found the total occlusion in common iliac,external iliac,femoral , femoral profound artery which were not detected in CTA. Aneurysm was detected similarly in both imaging methods. Arteries below the femur were well diagnosed as stenosis and total occlusion by MRA for anterior tibial, posterior tibial, and peroneal artery, however 6 cases gives negative results in popliteal artery CTA. CTA is limited in the evaluation of calcified lesions, where the high attenuation induces artifact that results in an overestimation of stenosis that reflect the false positive results. This effect becomes more relevant vessels below the femur, leading to a lower diagnostic performance of CTA. Our results indicate that MRA can overcome some limitations of CTA and result in improving the diagnostic confidence for evaluating lower extremity arteries. This make MRA a first-line diagnostic test for evaluation of lower extremity vessels, particularly in patients with known or suspected calcification or abnormal or asymmetric inflow patterns. The comparison done between the CTA technique are found to be interesting and MRA techniques help to reduce the limitations to CTA imposed by calcification.
Authors and Affiliations
Nouraldin Alhag Musa Mukhtar, Bushra Hussein Ahmed, Hussein Ahmed Hassan, Asma Ebrahim Mohammed, Caroline Edward Ayad
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