Diagnostic Utility of Various Techniques In Bone Tumors
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 1
Abstract
Background : Bone tumours are relatively uncommon. The precise incidence of specific bone tumours is not known, because many bone lesions are asymptomatic and are not biopsied. The initial work up and staging evaluation of a patient with a suspected bone tumour, particularly biopsy is a critical component of successful management. Aim :To assess the diagnostic accuracy of Fine needle aspirates and core needle biopsy of bone. The analysis compared with the accuracy according to anatomical location, size, type of lesion and histology. Materials and methods : 110 patients with bone tumours were referred to pathology department GMKMCH, Salem for diagnosis during the period from 2016 Nov to 2017 Nov. All had been examined by X-ray, CT, and (or) MRI, FNAB, CNB and excision biopsy with suspected local recurrence of primary malignant bone tumour (or) a metastatic lesion of a previously diagnosed malignancy were also included in this study. Results : Cytological diagnosis of 67/110 cases were compared with HPE after needle biopsy. Cytological diagnosis was correct for 76% of benign and 80% of malignant tumours. CNB was adequate in 96.7%. Sample for FNAC was obtained is 87.2%. The accuracy rate of open biopsy is almost 100%. Conclusion : The diagnostic accuracy of FNAC can be improved by the use of ancillary studies such as IHC, DNA cytometry, Karyotyping and medicular genetics in order to reduce the need for open biopsy of bone tumors.
Authors and Affiliations
Dr. M. Gunasundari
Keywords
Related Articles
- EP ID EP575990
- DOI 10.9790/0853-1701044851.
- Views 47
- Downloads 0
Diabetic Retinopathy and its Correlation with Thyroid Profile and Anti Thyroid Antibodies
Introduction: Diabetes mellitus and the eye diseases associated with it comprise a set of complex disorder with multi factorial etiology.1 Diabetic retinopathy ( DR ) is the most common complication of DM. It is seen tha...
Correlation between Liver Enzymes and Chronic Kidney Disease Iraqi Patients With or Without Hemodialysis
In CKD patients liver enzymes to be in the lower levels of normal reference range value, while ALP is high due to renal osteodystrophy. As a result the diagnosis and follow up of liver disease in these patients are dilem...
Study on Post-Exercise Blood Pressure Recovery Time in Individuals with Normal and High Body Mass Index
Post-exercise blood pressure change and its recovery time are considered to be an indicator of cardiovascular health. Obesity and hypertension are leading co morbidities associated with adverse cardiovascular events. The...
Value of MRUrethrographyin Comparison to Conventional RetrogradeUrethrography in the Surgical Treatment of Occlusive AnteriorUrethral Stricture
Objective: To prospectively assess the value of MR urethrography compared to conventional Retrograde urethrography in the surgical management of obliterative anterior urethral stricture. Materials And Methods: 15 male pa...
Retroperitoneal Sarcoma - A Clinico-Pathological Study
Retroperitoneal sarcomas are rare tumours that comprise approximately 15% of all soft tissue sarcomas in adults1 . Most of the retroperitoneal tumours are malignant and approximately one third is soft tissue sarcoma. Alt...