Diagnostic Value of Enhancement Pattern Approach with Contrast-enhanced 3D Gradient-Echo MR Imaging in characterization Focal Liver Lesions
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 7
Abstract
Objective: The purpose of this study was to assess standard dynamic liver MRI in characterization of focal liver lesions. Material: We retrospectively study all liver MRI studies performed in imaging center of Imam Khomeini hospital between November 11, 2014 and October 10, 2016. Demographic data of patients and laboratory findings were recorded.140 patients with22l liver lesion1foca liver tumors underwent 3-T MRI examination with TSE T2WI (TR = 2000 ms; TE = 100 ms); GE T1WI (TR=176ms; TE=90ms); Dynamic imaging using T1 THRIVE was performed after bolus injection of 0.1mmol/kg body weight of Gd-DTPA at a rate of 2ml/s, flushed with 20ml of sterile 0.9% saline solution through the antecubital vein. The results were compared to laboratory, histopathology and other previous radiological (US&/or MSCT) findings done for all patients. Results: Totally 221 hepatic lesions among 140 patients were assessed. Mean age of patients was 51.1±12.4 years [18-86]. Among the patients, 72 were female [51.4%] and 68 were male [48.6%] figure (25). 34 out of 221 lesions were found in cirrhotic liver [15%]. The analyzed lesions were hemangioma (n=81), cyst(n=24) ,FNH(n=9) ,adenoma (n=10),peliosishepatis(n=4),HCC(n=33),metastasis(n=58),cholangiocarcinoma(n=1),epit heliohemangioendothelioma(n=1). In our study Sensitivity, specificity, positive and negative predictive value and accuracy were respectively (98%, 97%, 96%, 98% and 98%). Conclusion: We hope to use standard dynamic MRI we could get enough information regarding characteristics of liver lesions (malignant or benign) to reduce number of biopsies and cost.
Authors and Affiliations
Arvin Arian, Hayder suhail Alareer, Farid Azmoudeh Ardalan
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