Clinicopathological Review Of Colorectal Cancer
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 3
Abstract
Background: Colorectal cancer is the third commonest cancer worldwide after cancer of the lungs and stomach in males and cancer of the breast and cervix in females.Surgical resection is the only treatment option with curative potential8,9. Adjuvant therapy is effective in prolonging survival and reducing disease progression in patients with colorectal cancer10 . Patients And Methods: This is an 8 year retrospective study of all patients with colorectal cancer admitted into the University of Port Harcourt Teaching Hospital (UPTH) between 1st January, 2008 to 31st December, 2016. Relevant data were retrieved and analysed using Statistical Package for Social Sciences (SPSS) version 16. Results: Seventy cases were analysed. There were 38 males and 32 females making a male to female ratio of 1.2:1. Their ages ranged from 23 to 82 with an average of 48.5± 3.7 years. The peak age was the 41-50 age range.The duration of symptoms before presentation at the hospital ranged from 1 week to 6 years.Adenocarcinoma was the commonest histological type, found in 56 (80%) followed by the mucinous carcinoma in 4 (5.7%) patients.Sixty four (91.4%) patients had surgical procedures done with abdominoperineal resection being the commonest and done in 18 (25.7%) patients.Post operative complications were recorded in 16 (22.9%) and 12 patients died giving a mortality rate of 17.1%. Conclusion: Colorectal cancers constitute a health burden in Port Harcourt with a significant number of cases seen in young people. Majority of the patients presented late and at advanced stages. Therefore, screening of high risk population, public enlightenment, early diagnosis and prompt treatment and follow up will reverse this trend.
Authors and Affiliations
Dodiyi-Manuel A. , Wichendu P. N.
Keywords
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- EP ID EP600268
- DOI 10.9790/0853-1603106366.
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